Knigth's move in the periodic table, from copper to platinum, novel antitumor mixed chelate copper compounds, casiopeinas, evaluated by an in vitro human and murine cancer cell line panel

Metal-Based Drugs

Volumn 8, Issue 1, 2001, Pages 19-28

  Gracia Mora, Isabel ^a   Ruiz Ramírez, Lena ^a   Gómez Ruiz, Celedonio ^a,b   Tinoco Méndez, Mabel ^a   Márquez Quiñones, Adriana ^a   Lira, Laura Romero De ^a   Marín Hernández, Álvaro ^a   Macías Rosales, Lucía ^a   Bravo Gómez, Ma Elena ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b INSTITUTO NACIONAL DE CANCEROLOGÍA   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC METAL COMPLEX; CASIOPEINA; CASIOPEINA I GLYCINE(4,7 DIPHENYL 1,10 PHENANTHROLINE)(GLYCINE)COPPER NITRATE; CASIOPEINA I SERINE(4,7 DIPHENYL 1,10 PHENANTHROLINE)(SERINE)COPPER NITRATE; CASIOPEINA II GLYCINE(4,7 DIMETHYL 1,10 PHENANTHROLINE)(GLYCINE)COPPER NITRATE; CASIOPEINA II GLYCINE(4,7 DIMETHYL 1,10 PHENANTHROLINE)(SERINE)COPPER NITRATE; CASIOPEINA III 5 ACETYLACETONATE(5 NITRO 1,10 PHENANTHROLINE)(ACETYLACETONATE)COPPER NITRATE; CASIOPEINA III E (4,7 DIMETHYL 1,10 PHENANTHROLINE)(ACETYLACETONATE)COPPER NITRATE; CASIOPEINA III I (4,4 DIMETHYL 2,2 BIPYRIDINE)(ACETYLACETONATE)COPPER NITRATE; CASIOPEINA IV GLYCINE(4,4 DIMETHYL 2,2 BIPYRIDINE)(GLYCINE)COPPER NITRATE; CASIOPEINA V GLYCINE(5 NITRO 1,10 PHENANTHROLINE)(GLYCINE)COPPER NITRATE; CASIOPEINA V SERINE(5 NITRO 1,10 PHENANTHROLINE)(SERINE)COPPER NITRATE; CASIOPEINAS; CISPLATIN; COPPER COMPLEX; METAL CHELATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LEWIS CARCINOMA; MELANOMA B16; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

EID: 0034921322     PISSN: 07930291     EISSN: None     Source Type: Journal    
DOI: 10.1155/MBD.2001.19     Document Type: Article

References (15)

1. Procedimiento para la obtención de complejos metálicos como agentes anticancerígenos
2. Procedimiento para la obtención de complejos metálicos como agentes anticancerígenos
3. Process to obtain new mixed copper aminoacidatecomplexes from phenylatephenanthroline to be used as anticancerigenic agents
4. Process to obtain new mixed copper aminoacidate from methylate phenantrholine complexes to be used as anticancerigenic agents
5. Aqua (1, 10- phenanthroline)(L-serinato)copper (II) Nitrate
6. Structural and reactivity studies on 4,4-dimethyl-2,2-bipyridine,acethylacetonate copper (II) nitrate (Casiopeina III-I) with DNA constituents, by UV-vis and EPR techniques
7. The antitumor activity of several transition metal complexes
8. Ternary copper complexes and manganese (III) tetrakis (4-benzoic acid)(porphirin) catalyze peroxynitrite-dependent nitration of aromatics
9. Induction of apoptosis by a novel copper-based anticancer compound- Casiopeina II in L1210 and CH1 cells
10. Cytostatic, mutagenic, antineoplastic activities and prelimina toxicity of copper (II) new drugs: Casiopeinas I, II and III
11. Protocols for sreening chemical agents and natural products against animal tumors and other biological systems. 3rd. ed
12. New colorimetric cytotoxity assay for antiancer drug screening
13. Comparison of in vitro anticancer drug screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines
14. Feasibility of drug sreening with panels of human tumor cell lines using a microculture tetrazolium assay