New treasures from old? EPHESUS

Cardiovascular Drugs and Therapy

Volumn 15, Issue 1, 2001, Pages 11-13

  Pfeffer, M A ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Aldosterone; Clinical trial; Eplerenone; Myocardial infarction; Spironolactone

Indexed keywords

EPLERENONE; SPIRONOLACTONE;

ALDOSTERONE BLOOD LEVEL; CLINICAL TRIAL; ENZYME INHIBITION; HEART INFARCTION; HEART LEFT VENTRICLE FAILURE; HUMAN; LUNG CONGESTION; PATHOGENESIS; PATIENT CARE; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SHORT SURVEY; SODIUM RETENTION;

ALDOSTERONE; ALDOSTERONE ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CLINICAL TRIALS; HEART FAILURE, CONGESTIVE; HUMANS; RENIN-ANGIOTENSIN SYSTEM; SPIRONOLACTONE;

EID: 0034921208     PISSN: 09203206     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011198432013     Document Type: Short Survey

References (20)

1. Angiotensin converting enzyme inhibition
2. The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy: The Collaborative Study Group
3. AT1-receptor blockers in hypertension and heart failure: Clinical experience and future directions
4. Valsartan in Acute Myocardial Infarction Trial (VALIANT): Rationale and design
5. Candesartan in heart failure - Assessment of reduction in mortality and morbidity (CHARM): Rationale and design
6. Comparison of the effects of losartan and captopril on mortality in patients after acute myocardial infarction: The OPTIMAAL trial design
7. Pathological hypertrophy and cardiac interstitium: Fibrosis and renin-angiotensin-aldosterone system
8. Myocardial fibrosis and the reninangiotensin-aldosterone system
9. Temporal differences in fibroblast proliferation and phenotype expression in response to chronic administration of angiotensin II or aldosterone
10. Inverse relationship between aldosterone and large artery compliance in chronically treated heart failure patients
11. Chronic administration of aldosterone depresses baroreceptor reflex function in the dog
12. Why does spironolactone improve mortality over and above an ACE inhibitor in chronic heart failure?
13. Effectiveness of spironolactone added to an angiotensin-converting enzyme inhibitor and a loop diuretic for severe chronic congestive heart failure (the randomized aldactone evaluation study [RALES])
14. The EPHESUS trial: Eplerenone in patients with heart failure due to systolic dysfunction complicating acute myocardial infarction (Eplerenone's neuro Hormonal Efficacy and Survival Study)
15. Inhibition of myocardial endothelin pathway improves long-term survival in heart failure
16. A receptor blockade prevents left ventricular remodeling and deterioration of cardiac function in experimental heart failure
17. Rouleau JL. Endothelin A receptor blockade causes adverse left ventricular remodeling but improves pulmonary artery pressure after infarction in the rat
18. Endothelin-A receptor antagonism during acute myocardial infarction in rats
19. Aldosterone inhibition limits collagen synthesis and progressive left ventricular enlargement after anterior myocardial infarction