Transcriptional regulation by changes in tonicity

Kidney International

Volumn 60, Issue 2, 2001, Pages 408-411

  Handler, J S ^a   Kwon, H M ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Betaine; Calcineurin; Cyclosporine A; Myoinositol; Sorbitol; Taurine; TonEBP

Indexed keywords

BINDING PROTEIN;

ANIMAL CELL; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENE SEQUENCE; GENE TRANSLOCATION; GENETIC TRANSCRIPTION; KIDNEY MEDULLA; MACROMOLECULE; NONHUMAN; PRIORITY JOURNAL; RAT; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

EID: 0034919289     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2001.060002408.x     Document Type: Conference Paper

References (27)

1. Intra- and extracellular element concentrations of rat renal papilla in antidiuresis
2. Living with water stress: Evolution of osmolyte system
3. Osmoregulation of GPC: Choline phosphodiesterase in MDCK cells: Different effects of urea and NaCl
4. The tonicity-sensitive element that mediates increased transcription of the betaine transporter gene in response to hypertonic stress
5. ORE, a eukaryotic minimal essential osmotic response element: The aldose reductase gene in hyperosmotic stress
6. Isolation of the mouse aldose reductase promoter and identification of a tonicity-responsive element
7. Identification and characterization of multiple osmotic response sequences in the human aldose reductase gene
8. Transcription of the sodium/ myo-inositol cotransporter gene is regulated by multiple tonicity-responsive enhancers spread over 50 kilobase pairs in the 5′-flanking region
9. Tonicity-responsive enhancer binding protein, a Rel-like protein that stimulates transcription in response to hypertonicity
10. NFAT5, a constitutively nuclear FNAT protein that does not cooperate with Fos and Jun
11. The NFAT-related protein NFATL1 (TonEBP/NFAT5) is induced upon t cell activation in a calcineurin-dependent manner
12. NFATz: A novel rel similarity domain containing protein
13. Purification, identification, and characterization of an osmotic response element binding protein
14. Tyrosine kinase inhibitors and immunosuppressants perturb the myo-inositol but not the betaine cotransporter in isotonic and hypertonic MDCK cells
15. Hypertonicity-induced phosphorylation and nuclear localization of the transcription factor TonEBP
16. Nuclear redistribution of tonicity-responsive enhancer binding protein requires prosteasome activity
17. Bidirectional regulation of tonicity-responsive enhancer binding protein in response to changes in tonicity
18. Purification and reconstitution of an osmosensor: Transporter Prop of Escherichia coli senses and responds to osmotic shifts
19. Phosphorylation stimulates the cooperative DNA-binding properties of the transcription factor OmpR
20. Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 "two-component" osmosenor
21. Shrinkage-induced protein tyrosine phosphorylation in Chinese hamster ovary cells
22. + exchanger activation during shrinkage of human neutrophils
23. Protection of renal inner medullary epithelial cells from apoptosis by hypertonic stress-induced p53 activation
24. Hyperosmolality causes growth arrest of murine kidney cells induction of GADD45 and GADD153 by osmosensing via stress-activated protein kinase 2
25. Signal for induction of aldose reductase in renal medullary cells by high external NaCl
26. --dependent taurine transporter that is regulated by hypertonicity
27. Intracellular betaine substitutes for sorbitol in protecting renal medullary cells from hypertonicity