A polymorphic marker for the human cathepsin B gene

Molecular and Cellular Probes

Volumn 15, Issue 4, 2001, Pages 235-237

  MacKenzie, J R ^a   Mason, Sue L ^b   Hickford, Jon G H ^b   Kohonen Corish, Maija R J ^c   Bickerstaffe, Roy ^b  

^a Biology and Environment   (Australia)

^b LINCOLN UNIVERSITY   (New Zealand)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Cancer; Cathepsin; Gene; Human; PCR; Polymorphism; Proteolytic

Indexed keywords

CATHEPSIN B;

ALLELE; ARTICLE; CANCER; CHROMOSOME 8; CHROMOSOME MAP; EXON; GENE FREQUENCY; GENETIC LINKAGE; GENETIC POLYMORPHISM; HETEROZYGOSITY; INTRON; MARKER GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEGRADATION;

EID: 0034918719     PISSN: 08908508     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcpr.2001.0362     Document Type: Article

References (26)

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2. Cathepsin B activity in normal human osteoblast-like cells and human osteoblastic osteosarcoma cells (MG-63): Regulation by interleukin-1 beta and parathyroid hormone
3. Lysosomal proteases cathepsins D, B, H, L and their inhibitors stefins A and B in head and neck cancer
4. Variable expression of cathepsin B and D correlates with highly invasive and metastatic phenotype of oral cancer
5. Localization of cathepsin B in two human lung cancer cell lines
6. Immunohistochemical study of cathepsin B. Prognostic significance in human lung cancer
7. Cytochemical and biochemical evidence of cathepsin B in malignant, transformed and normal breast epithelial cells
8. Cathepsin B in human breast tumor tissue and cancer cells
9. Stefins and lysosomal cathepsins B, L and D in human breast carcinoma
10. Prognostic value of the cysteine proteases cathepsins B and cathepsin L in human breast cancer
11. High levels of cathepsin B predict poor outcome in patients with breast cancer
12. Cysteine endopeptidase activity levels in normal human tissues, colorectal adenomas and carcinomas
13. Stage-specific increases in cathepsin B messenger RNA content in human colorectal carcinoma
14. Cathepsin B expression in colorectal carcinomas correlates with tumor progression and shortened patient survival
15. Increased gelatinase A (MMP-2) and cathepsin B activity in invasive tumor regions of human colon cancer samples
16. Expression of cathepsin B and cystatin C in human colorectal cancer
17. Serum cathepsin B levels and urinary excretion of cathepsin B in the cancer patients with remote metastasis
18. Cathepsin B activity in human lung tumor cell lines: Ultrastructural localization, pH sensitivity, and inhibitor status at the cellular level
19. Cathepsin B expression and its correlation with tumor-associated laminin and tumor progression in gastric cancer
20. A Taql DNA polymorphism in the human cathepsin B gene (CTSB)
21. Human gastric adeno-carcinoma cathepsin B: Isolation and sequencing of full-length cDNAs and polymorphisms of the gene
22. Variant cathepsin B activity secreted from human pancreatic cancer cell lines into protein-free chemically defined medium
23. Characterization of the cathepsin B gene and multiple mRNAs in human tissues: Evidence for alternative splicing of cathepsin B pre-mRNA
24. Identification of two new exons and multiple transcription start points in the 5′-untranslated region of the human cathepsin-B-encoding gene
25. Expression of lysosomal cathepsin B during calf myoblast-myotube differentiation. Characterization of a cDNA encoding bovine cathepsin B
26. Confirmation of the human cathepsin B gene (CTSB) assignment to chromosome 8