Linkage and association studies of prostate cancer susceptibility: Evidence for linkage at 8p22-23

American Journal of Human Genetics

Volumn 69, Issue 2, 2001, Pages 341-350

  Xu, J ^a   Zheng, S L ^a   Hawkins, G A ^a   Faith, D A ^a   Kelly, B ^a   Isaacs, S D ^a   Wiley, K E ^a   Chang, B L ^a   Ewing, C M ^a   Bujnovszky, P ^a   Carpten, J D ^a   Bleecker, E R ^a   Walsh, P C ^a   Trent, J M ^a   Meyers, D A ^a   Isaacs, W B ^a  

^a JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER SUSCEPTIBILITY; CHROMOSOME 8P; FAMILIAL CANCER; GENE FREQUENCY; GENE LOCATION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; HOMOZYGOSITY; HUMAN; JEW; MAJOR CLINICAL STUDY; MALE; PEDIGREE; PRIORITY JOURNAL; PROSTATE CANCER;

EID: 0034918268     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/321967     Document Type: Article

References (36)

1. Physical mapping of chromosome 8p22 markers and their homozygous deletion in a metastatic prostate cancer
2. Tumor suppressor genes in prostate cancer
3. Comprehensive human genetic maps: Individual and sex-specific variation in recombination
4. Loss of heterozygosity on the short arm of chromosome 8 in male breast carcinomas
5. Human epithelial ovarian cancer allelotype
6. Faster sequential genetic linkage computations
7. Deletion mapping in colorectal cancer of a putative tumour suppressor gene in 8p22-p21.3
8. Allelic imbalance and microsatellite instability in prostatic adenocarcinoma
9. Allelic loss detected on chromosomes 8, 10, and 17 by fluorescence in situ hybridization using single-copy P1 probes on isolated nuclei from paraffin-embedded prostate tumors
10. Frequent loss of heterozygosity for loci on chromosome 8p in hepatocellular carcinoma, colorectal cancer, and lung cancer
11. Distribution of the admixture test for the detection of linkage under heterogeneity
12. A genomic scan of families with prostate cancer identifies multiple regions of interest
13. The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumors
14. Homozygous deletions at 8p22 and 8p21 in prostate cancer implicate these regions as the sites for candidate tumor suppressor genes
15. Deletion mapping of chromosome 8 in cancers of the urinary bladder using restriction fragment length polymorphisms and microsatellite polymorphisms
16. Allele-sharing models: LOD scores and accurate linkage tests
17. Parametric and nonparametric linkage analysis: A unified multipoint approach
18. Implementing a unified approach to family-based test of association
19. Construction of multilocus genetic linkage maps in humans
20. Genetic dissection of complex traits: Guideline for interpreting and reporting linkage results
21. Strategies for multilocus linkage analysis in humans
22. Structure and methylation-associated silencing of a gene within a homozygously deleted region of human chromosome band 8p22
23. Evidence for three tumor suppressor gene loci on chromosome 8p in human prostate cancer
24. Homozygous and frequent deletion of proximal 8p sequences in human prostate cancers: Identification of a potential tumor suppressor gene site
25. Loss of heterozygosity studies in squamous cell carcinomas of the head and neck
26. Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genome-wide search
27. Analysis of 99 microdissected prostate carcinomas reveals a high frequency of allelic loss on chromosome 8p12-21
28. N-Acetyltransferase expression and DNA binding of N-hydroxyheterocyclic amines in human prostate epithelium
29. A class of tests for linkage using affected pedigree members
30. Sequence variants of DLC1 in colorectal and ovarian tumours
31. Allelic losses at chromosome 8p21-23 are early and frequent events in the pathogenesis of lung cancer
32. Assignment and cloning of mouse Arhgap7 to chromosome 8A4-B2, a conserved syntenic region of human chromosome 8p22→p21
33. Exact tests for association between alleles at arbitrary numbers of loci