Effects of chemical modifications of crotoxin B, the phospholipase A2 subunit of crotoxin from Crotalus durissus terrificus snake venom, on its enzymatic and pharmacological activities

International Journal of Biochemistry and Cell Biology

Volumn 33, Issue 9, 2001, Pages 877-888

  Soares, Andreimar M ^a,b   Mancin, Adriana C ^a   Cecchini, Alessandra L ^a   Arantes, Eliane C ^a   França, Suzelei C ^b   Gutiérrez, José M ^c   Giglio, José R ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF RIBEIRÃO PRETO   (Brazil)

^c UNIVERSIDAD DE COSTA RICA   (Costa Rica)

Author keywords

Bactericidal action; Chemical modifications; Crotalus durissus terrificus; Crotoxin B; Myotoxic phospholipase A2; Pharmacological activities

Indexed keywords

2 NITROBENZENESULFONYLFLUORIDE; 2 NITROPHENYLSULFENYLCHLORIDE; 4 BROMOPHENACYL BROMIDE; ACETIC ANHYDRIDE; CROTOXIN; CROTOXIN B; CYANOGEN BROMIDE; EDETIC ACID; FLUORIDE; HISTIDINE; LIPOSOME; LYSINE; PHOSPHOLIPASE A2; SNAKE VENOM; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG;

ACETYLATION; ALKYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICOAGULATION; ARTICLE; BACTERICIDAL ACTIVITY; CATALYSIS; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; EDEMA; ENZYME ACTIVITY; LETHALITY; MALE; MOUSE; MUSCLE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN MODIFICATION; TOXICITY;

AMINO ACID SEQUENCE; ANIMALS; ANTI-BACTERIAL AGENTS; ANTICOAGULANTS; CREATINE KINASE; CROTALID VENOMS; CROTALUS; CROTOXIN; EDEMA; ESCHERICHIA COLI; HEMOLYSIS; KINETICS; LETHAL DOSE 50; LIPOSOMES; MICE; MOLECULAR SEQUENCE DATA; PEROXIDASES; PHOSPHOLIPASES A; PROTEIN SUBUNITS;

EID: 0034918136     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(01)00065-6     Document Type: Article

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