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Volumn 52, Issue 2, 2001, Pages 149-156

Fotemustine combined with procarbazine in recurrent malignant gliomas: A phase I study with evaluation of lymphocyte O6-alkylguanine-DNA alkyltransferase activity

(8) Boiardi, A a Silvani, A a Ciusani, E a Watson, A b Margison, G b Berger, E c Lucas, C c Giroux, B c

a DEPARTMENT OF NEUROSURGERY (Italy)

b CHRISTIE HOSPITAL (United Kingdom)

c INSTITUT DE RECHERCHES INTERNATIONALES SERVIER (France)

Author keywords

Fotemustine; Malignant glioma; O6 alkylguanine DNA alkyltransferase; Phase I study; Procarbazine

Indexed keywords

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; CORTICOSTEROID; FOTEMUSTINE; NITROSOUREA DERIVATIVE; PROCARBAZINE;

ADULT; AGED; ANEMIA; ARTICLE; BONE MARROW SUPPRESSION; CANCER CONTROL; CANCER RECURRENCE; CANCER SURVIVAL; CLINICAL ARTICLE; CLINICAL TRIAL; DEPLETION; DISEASE COURSE; DOSE CALCULATION; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG TOLERABILITY; ENZYME ACTIVITY; FEMALE; GLIOMA; HUMAN; LYMPHOCYTE FUNCTION; MAINTENANCE THERAPY; MAXIMUM TOLERATED DOSE; NEUTROPENIA; PHASE 1 CLINICAL TRIAL; THROMBOCYTOPENIA; VALIDATION PROCESS;

ADULT; AGED; ANTINEOPLASTIC AGENTS; BRAIN NEOPLASMS; FEMALE; GLIOMA; HUMANS; LYMPHOCYTES; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NITROSOUREA COMPOUNDS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; ORGANOPHOSPHORUS COMPOUNDS; PROCARBAZINE;

EID: 0034915241 PISSN: 0167594X EISSN: None Source Type: Journal
DOI: 10.1023/A:1010626421709 Document Type: Article

Times cited : (13)

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