The function of leak and kuzbanian during growth cone and cell migration

Mechanisms of Development

Volumn 106, Issue 1-2, 2001, Pages 25-36

  Schimmelpfeng, K ^a   Gogel S ^a   Klambt C ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Drosophila; Kuzbanian; Leak; Robo; Slit

Indexed keywords

FASCICLIN II; METALLOPROTEINASE;

ALLELE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL GROWTH; CELL MIGRATION; DROSOPHILA; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; GROWTH CONE; MUSCLE CELL; MUTANT; NERVE FIBER; NERVE GROWTH; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; AXONS; CELL ADHESION MOLECULES, NEURONAL; CELL MOVEMENT; CENTRAL NERVOUS SYSTEM; DISINTEGRINS; DROSOPHILA; DROSOPHILA PROTEINS; ECTODERM; EMBRYONIC DEVELOPMENT; GENES, INSECT; GENETIC COMPLEMENTATION TEST; GROWTH CONES; HEAD; METALLOENDOPEPTIDASES; MODELS, BIOLOGICAL; MORPHOGENESIS; NERVE TISSUE PROTEINS; RECEPTORS, IMMUNOLOGIC;

EID: 0034914811     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(01)00402-6     Document Type: Article

References (55)

1. Chimeric axon guidance receptors: the cytoplasmic domains of slit and netrin receptors specify attraction versus repulsion
2. Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor
3. Axon repulsion from the midline of the Drosophila CNS requires slit function
4. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
5. Slit proteins: key regulators of axon guidance, axonal branching, and cell migration
6. Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance
7. Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor
8. DCC and netrins
9. The cell surface metalloprotease/disintegrin Kuzbanian is required for axonal extension in Drosophila
10. Calmodulin and son of sevenless dependent signaling pathways regulate midline crossing of axons in the Drosophila CNS
11. Embryonic development of the Drosophila central nervous system
12. Genetic analysis of growth cone guidance in Drosophila: fasciclin II functions as a neuronal recognition molecule
13. Axon guidance: netrin receptors are revealed
14. Regulated cleavage of a contact-mediated axon repellent
15. A ligand gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin induced growth cone attraction to repulsion
16. Calcium signalling in the guidance of nerve growth by netrin-1
17. Growth-cone attraction to netrin-1 is converted to repulsion by laminin-1
18. Chemorepulsion of neuronal migration by Slit2 in the developing mammalian forebrain
19. Commissure formation in the embryonic CNS of Drosophila: I. Identification of the required gene functions
20. Commissure formation in the embryonic CNS of Drosophila: II. Function of the different midline cells
21. Delta-1 activation of notch-1 signaling results in HES-1 transactivation
22. The terminal regions of the body pattern
23. Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors
24. Dosage sensitive and complementary functions of roundabout and commissureless control axon crossing of the CNS midline
25. Slit is the midline repellent for the robo receptor in Drosophila
26. Complex proteolytic processing acts on Delta, a transmembrane ligand for Notch, during Drosophila development
27. Control of cell behaviour by signalling through Eph receptors and ephrins
28. CNS midline cells in Drosophila induce the differentiation of lateral neural cells
29. Phospholipase C gamma and phosphoinositide 3 kinase mediate cytoplasmic signaling in nerve growth cone guidance
30. cAMP dependent growth cone guidance by netrin 1
31. Effects of roundabout on growth cone dynamics, filopodial length, and growth cone morphology at the midline and throughout the neuropile
32. Molecular basis of semaphorin-mediated axon guidance
33. Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. I. Zygotic loci on the second chromosome
34. Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis
35. Neurobiology. Turning attraction into repulsion
36. Processing of the notch ligand delta by the metalloprotease Kuzbanian
37. Crossing the midline: roles and regulation of Robo receptors
38. Selecting a longitudinal pathway: Robo receptors specify the lateral position of axons in the Drosophila CNS
39. KUZ, a conserved metalloprotease disintegrin protein with two roles in Drosophila neurogenesis
40. slit: an EGF-homologous locus in Drosophila melanogaster involved in the development of the embryonic central nervous system
41. slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains
42. Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding
43. Mutations affecting growth cone guidance in Drosophila: genes necessary for guidance toward or away from the midline
44. Short-range and long-range guidance by Slit and its Robo receptors: a combinatorial code of Robo receptors controls lateral position
45. Short-range and long-range guidance by Slit and its Robo receptors: Robo and Robo2 play distinct roles in midline guidance
46. Structural features of a superfamily of zinc-endopeptidases: the metzincins
47. Receptor tyrosine phosphatases regulate axon guidance across the midline of the Drosophila embryo
48. A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback
49. commissureless controls growth cone guidance across the CNS midline in Drosophila and encodes a novel membrane protein
50. The molecular biology of axon guidance
51. Directional guidance of neuronal migration in the olfactory system by the protein Slit
52. Semaphorin signaling: a little less per-plexin
53. The mouse SLIT family: secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis and axon guidance
54. The conserved immunoglobulin superfamily member SAX 3/Robo directs multiple aspects of axon guidance in C. elegans