Binding of phosphate and pyrophosphate ions at the active site of human angiogenin as revealed by X-ray crystallography

Protein Science

Volumn 10, Issue 8, 2001, Pages 1669-1676

  Leonidas, Demetres D ^a,c   Chavali, Gayatri B ^a   Jardine, Anwar M ^b   Li, Songlin ^a,d   Shapiro, Robert ^b   Acharya, K Ravi ^a  

^a University of Bath   (United Kingdom)

^b HARVARD MEDICAL SCHOOL   (United States)

^c INSTITUTE OF BIOLOGY   (Greece)

^d University of Alabama at Birmingham   (United States)

Author keywords

Angiogenin; Inhibitor design; Phosphate binding; Ribonuclease A; X ray crystallography

Indexed keywords

ANGIOGENIN; PANCREATIC RIBONUCLEASE; PHOSPHATE; PYROPHOSPHATE; RIBONUCLEASE A;

ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; HYDROGEN BOND; PRIORITY JOURNAL; RNA BINDING; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DIPHOSPHATES; HUMANS; HYDROGEN BONDING; IONS; MODELS, MOLECULAR; PHOSPHATES; PROTEIN BINDING; PROTEIN CONFORMATION; RIBONUCLEASE, PANCREATIC;

BOVINAE;

EID: 0034913990     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.13601     Document Type: Article

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