No linkage and association of atopy to chromosome 16 including the interleukin-4 receptor gene

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 56, Issue 8, 2001, Pages 775-779

  Haagerup, A ^a,b   Bjerke, T ^a,b   Schiotz P O ^a,b   Dahl, R ^a,b   Binderup, H G ^a,b   Kruse, T A ^a,b,c  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c ODENSE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Allergy; Association; Atopy; Chromosome 16; Genetics; Linkage

Indexed keywords

INTERLEUKIN 4 RECEPTOR; MICROSATELLITE DNA;

ARTICLE; ATOPY; CHROMOSOME 16; DENMARK; FAMILY STUDY; GENE MAPPING; GENETIC LINKAGE; GENETIC PREDISPOSITION; GENOTYPE; HUMAN; IMMEDIATE TYPE HYPERSENSITIVITY; INHERITANCE; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; RADIOALLERGOSORBENT TEST;

CHILD; CHROMOSOMES, HUMAN, PAIR 16; FEMALE; HUMANS; HYPERSENSITIVITY; LINKAGE (GENETICS); LOD SCORE; MALE; RECEPTORS, INTERLEUKIN-4; VARIATION (GENETICS);

EID: 0034913627     PISSN: 01054538     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1398-9995.2001.056008775.x     Document Type: Article

References (21)

1. Common polymorphisms in the coding part of the IL4-receptor gene
2. The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor
3. The polymorphisms S503P and Q576R in the interleukin-4 receptor alpha gene are associated with atopy and influence the signal transduction
4. Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations
5. The R576 IL-4 receptor alpha allele correlates with asthma severity
6. The interleukin-4 receptor variant Q576R in hyper-IgE syndrome
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