UV light does not induce p53 mutation in melanocytes in vitro [1]

Dermatology

Volumn 202, Issue 4, 2001, Pages 339-340

  Tronnier, Michael ^a   Alexander, M ^a   Lontz W ^a   Brinckmann, J ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

Author keywords

Melanocytes, human; p53 gene; Point mutation

Indexed keywords

PROTEIN P53;

CONTROLLED STUDY; GENE MUTATION; HUMAN; HUMAN CELL; LETTER; MELANOCYTE; NEWBORN; PATHOGENESIS; POINT MUTATION; PRIORITY JOURNAL; SUN EXPOSURE; SUPPRESSOR GENE; ULTRAVIOLET A RADIATION; ULTRAVIOLET B RADIATION; ULTRAVIOLET RADIATION;

CELLS, CULTURED; DNA; GENES, P53; HUMANS; MELANOCYTES; MUTATION; POLYMERASE CHAIN REACTION; ULTRAVIOLET RAYS;

EID: 0034912828     PISSN: 10188665     EISSN: None     Source Type: Journal    
DOI: 10.1159/000051671     Document Type: Letter

References (11)

1. p53 mutations in human cancers
2. High levels of p53 protein in UV-irradiated normal human skin
3. A role for sunlight in skin cancer: UV induced p53 mutation in squamous cell carcinoma
4. Mutation hotspot due to sunlight in the p53 gene of nonmelanoma skin cancers
5. p53 protects against skin cancer induction by UV-B radiation
6. TP53 tumor suppressor gene and skin carcinogenesis
7. Detection of p53 mutations in benign and dysplastic nevi
8. ink4a and p53 genes in sporadic dysplastic nevus
9. Detection of single base substitutions by ribonuclease cleavage at mismatches in RNA:DNA duplexes
10. Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium
11. Role of p53 in UVB-induced apoptosis in human HaCaT keratinocytes