Use of primed in situ labeling (PRINS) for the detection of telomeric deletions associated with mental retardation

Cytogenetics and Cell Genetics

Volumn 93, Issue 1-2, 2001, Pages 16-18

  Bonifacio, S ^a   Centrone, C ^a   Da Prato, L ^b   Scordo, M R ^a   Estienne, M ^c   Torricelli, Francesca ^a  

^a CAREGGI UNIVERSITY HOSPITAL   (Italy)

^b SDS/GA Core Laboratory   (Italy)

^c DEPARTMENT OF NEUROSURGERY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHILD; CHROMOSOME ANALYSIS; CONTROLLED STUDY; CYTOGENETICS; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DELETION; GENE REARRANGEMENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MENTAL DEFICIENCY; PRIMED IN SITU LABELING; PRIORITY JOURNAL; REPRODUCIBILITY; TELOMERE;

EID: 0034908961     PISSN: 03010171     EISSN: None     Source Type: Journal    
DOI: 10.1159/000056939     Document Type: Article

References (8)

1. Structure and function of telomeres
2. The detection of subtelomeric chromosomal rearrangements in idiopathic mental retardation
3. Del(18p) shown to be a cryptic translocation using a multiprobe FISH assay for subtelomeric chromosome rearrangements
4. Development and clinical application of an innovative fluorescence in situ hybridization technique which detects submicroscopic rearrangements involving telomeres
5. Oligonucleotide-priming methods for the chromosome-specific labeling of alpha satellite DNA in situ
6. A complete set of human telomeric probes and their clinical application
7. Screening for submicroscopic chromosome rearrangements in children with idiopathic mental retardation using microsatellite markers for the chromosome telomeres
8. Staining of human telomeres with primed in situ labeling (PRINS)