Combination of benzo[a]phenothiazines with acyclovir against herpes simplex virus

International Journal of Antimicrobial Agents

Volumn 18, Issue 1, 2001, Pages 67-72

  Mucsi, Ilona ^a   Molnár, Joseph ^a   Motohashi, Noboru ^b  

^a UNIVERSITY OF SZEGED   (Hungary)

^b MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

ACV; Benzo a phenothiazines; Combination; Herpes simplex virus; Synergism

Indexed keywords

5 OXO 5H BENZO[A]PHENOTHIAZINE; 6 METHYL 5 OXO 5H BENZO[A]PHENOTHIAZINE; ACICLOVIR; BENZO[A]PHENOTHIAZINE; PHENOTHIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG POTENTIATION; DRUG SENSITIVITY; HERPES SIMPLEX VIRUS 2; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; STRAIN DIFFERENCE; VERO CELL; VIROGENESIS; VIRUS CULTURE; VIRUS TITRATION;

ACYCLOVIR; ANIMALS; ANTIVIRAL AGENTS; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; DRUG SYNERGISM; HERPESVIRUS 2, HUMAN; MICROBIAL SENSITIVITY TESTS; PHENOTHIAZINES; PLAQUE ASSAY; SERIAL PASSAGE; VERO CELLS;

EID: 0034908503     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-8579(01)00323-5     Document Type: Article

References (27)

1. Antibacterial effect of some phenothiazine compounds and the R-factor elimination by chlorpromazine
2. Antiplasmid activity of phenothiazines, benzo[a]phenothiazines and benz[c]acridines
3. Inhibition of the adhesion of E. coli on cultured human epithelial cells in the presence of promethazine or imipramine
4. Antimicrobial activity of phenothiazines, benzo[a]phenothiazines and benz[c]acridines
5. Induction of anti-Escherichia coli activity in mice by phenothiazines, benzo[a]phenothiazines and benz[c]acridines
6. Cytotoxicity and differentiation-inducing activity of phenothiazine and benzo[a]phenothiazine derivatives
7. Inhibition of arenavirus multiplication in vitro by phenothiazines
8. Antiviral activity of phenothiazine and benzo[a]phenothiazine derivatives
9. Antimutagenicity of benzo[a]phenothiazines in chemically induced mutagenesis
10. Antiviral resistance - An emerging problem
11. Drug resistance patterns of herpes simplex virus isolated from patients treated with acyclovir
12. Acyclorvir-resistance herpes simplex virus infections in patients with the acquired immunodeficiency syndrome
13. In vitro and in vivo characterization of herpes simplex virus clinical isolated recovered from patients infected with human immunodeficiency virus
14. Evaluation of antiherpes virus drug combinations. Virazole plus arabinofuranosylhypo-xanthine and virazole plus arabinofuranosyladenine
15. Consensus symposium on combined antiviral therapy
16. Test for antitumor activities of phenothiazines and phenoxazines
17. A simple method of estimating fifty percent end points
18. Synergistic activity of combinations of recombinant human alpha interferon and acyclovir, administered concomitantly and in sequence, against a lethal herpes simplex virus type 1 infection in mice
19. Combined antiviral effect of interferon and acyclovir on herpes simplex virus type 1 and 2
20. Effect of combinations of acyclovir with vidarabine or its 5′-monophosphate on herpes simplex viruses in cell culture and in mice
21. Synergism between recombinant human interferon and nucleoside antiviral agents against herpes simplex virus: Examination with an automated microtiter plate assay
22. Synergistic interaction between interferon-α and acyclovir in the treatment of herpes simplex virus type 1 infection in mice
23. Synergistic therapy by acyclovir and A1110U for mice orofacially infected with herpes simplex viruses
24. Combination therapy of recombinant human alpha 2 interferon and acyclovir in the treatment of herpes simplex keratitis
25. Acyclovir enhances the antiviral effect of interferon in chronic hepatitis B
26. Mechanism of action and selectivity of acyclovir
27. Molecular mechanism of antiviral resistance