Characterization of Ascaris-induced biphasic skin allergic reaction model in mice: Possible roles of mast cells in early-phase and CD4-positive T cells in late-phase reactions

Pharmacology

Volumn 63, Issue 2, 2001, Pages 82-89

  Sengoku, Takanori ^a   Sato, Sachio ^a   Sakuma, Shozo ^a   Ogawa, Toshikazu ^a   Ohkubo, Yoshitaka ^a   Goto, Toshio ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Biphasic skin reaction; CD4 positive T cell; Ear edema; Eosinophil; Histamine; Immunoglobulin E; Interleukin 4; Interleukin 5; Mast cell; WBB6F1 W WV mice

Indexed keywords

INTERLEUKIN 4; INTERLEUKIN 4 ANTIBODY; INTERLEUKIN 5; INTERLEUKIN 5 ANTIBODY; T LYMPHOCYTE ANTIBODY; TRANILAST;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASCARIS; CELL INFILTRATION; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; EAR DISEASE; EDEMA; EOSINOPHILIA; FEMALE; HISTAMINE RELEASE; MAST CELL DEGRANULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN ALLERGY; T LYMPHOCYTE;

ANIMALS; ASCARIS; CD4-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; EAR; EDEMA; EOSINOPHILS; FEMALE; HISTAMINE RELEASE; HYPERSENSITIVITY; HYPERSENSITIVITY, DELAYED; HYPERSENSITIVITY, IMMEDIATE; INTERLEUKIN-4; INTERLEUKIN-5; MAST CELLS; MICE; MICE, INBRED BALB C; SKIN TESTS;

EID: 0034905230     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000056117     Document Type: Article

References (24)

1. The structure and morphology of normal and atopic eczema
2. Lesional expression of interferon-γ in atopic eczema
3. Analysis of the cytokine pattern expressed in situ in inhalant allergen patch test reactions of atopic dermatitis patients
4. Differential in situ cytokine gene expression in acute versus chronic atopic dermatitis
5. + T cells
6. Biphasic response against aeroallergen in atopic dermatitis showing a switch from an initial Th2 response to a Th1 response in situ: An immunocytochemical study
7. Chronologic analysis of in situ cytokine expression in mite allergen-induced dermatitis in atopic subjects
8. Activation of mast cells for mediator release through IgE receptors
9. The late phase of the immunoglobulin E-mediated reaction: A link between anaphylaxis and common allergic disease?
10. Mediators of allergic inflammation in the skin
11. Pharmacological characterization of mouse ear PCA
12. Dexamethasone or cyclosporin A suppress mast cell-leukocyte cytokine cascades: Multiple mechanisms of inhibition of IgE- and mast cell-dependent cutaneous inflammation in the mouse
13. Detection of IgE antibody-forming cells by passive cutaneous anaphylaxis using cell extract from lymphoid organ
14. Effect of tacrolimus hydrate (FK506) ointment on spontaneous dermatitis in NC/Nga mice
15. Study of the mechanism of inhibitory action of tranilast on chemical mediator release
16. Regulation of murine IgE production in SJA/9 and nude mice: Potentiation of IgE production by recombinant interleukin 4
17. Experimental pulmonary eosinophilia in mice by Ascaris suum extract
18. Effects of tacrolimus ointment on type I (immediate and late) and IV (delayed) cutaneous allergic reactions in mice
19. Critical protective role of mast cells in a model of acute septic peritonitis
20. Induction of eczematous skin reaction in experimentally induced hyperplastic skin of Balb/c mice by monoclonal anti-DNP IgE antibody: Possible implications for skin lesion formation in atopic dermatitis
21. An immunopharmacological study of the biphasic allergic skin reaction in mice
22. Successful treatment of resistant facial lesions of atopic dermatitis with 0.1% FK506 ointment
23. Tacrolimus ointment for atopic dermatitis
24. A short-term trial of tacrolimus ointment for atopic dermatitis