Chalcones as potent antiplatelet agents and calcium channel blockers

Drug Development Research

Volumn 53, Issue 1, 2001, Pages 9-14

  Lin, Chun Nan ^a   Hsieh, Hsin Kaw ^a   Ko, Horng Huey ^a   Hsu, Mei Feng ^a   Chang, Ya Ling ^a   Chung, Mei Ing ^a   Kang, Jaw Jou ^a   Wang, Jih Pyang ^a   Teng, Che Ming ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Antiplatelet; Calcium channel blocker; Chalcones; Cyclooxygenase; Vasorelaxing

Indexed keywords

ACETYLSALICYLIC ACID; ADRENALIN; ANTITHROMBOCYTIC AGENT; ARACHIDONIC ACID; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; CHALCONE DERIVATIVE; INDOMETACIN; PHENYLEPHRINE; POTASSIUM ION; PROSTAGLANDIN SYNTHASE INHIBITOR; THROMBOXANE;

ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; ENZYME INHIBITION; FEMALE; MALE; NONHUMAN; RABBIT; RAT; STRUCTURE ACTIVITY RELATION; THORACIC AORTA; THROMBOCYTE AGGREGATION INHIBITION; VASODILATATION; VOLTAGE CLAMP;

EID: 0034904420     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.1163     Document Type: Article

References (2)

1. Bohr DH. 1963. Vascular smooth muscle: dual effect of calcium. Science 139:597-599.
2. Egan RW, Paxten J, Kurhl FA. 1976. Mechanism for irreversible self-deactivation of prostaglandin synthase. J Biol Chem 251:7329-7335.