Effects of physical properties of powder particles on binder liquid requirement and agglomerate growth mechanisms in a high shear mixer

European Journal of Pharmaceutical Sciences

Volumn 14, Issue 2, 2001, Pages 135-147

  Johansen, Anita ^a   Schafer, Torben ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Agglomerate growth mechanisms; Binder liquid requirement; Binder viscosity; High shear mixer; Melt agglomeration; Powder particle properties

Indexed keywords

AGGLOMERATION; BINDERS; COALESCENCE; PARTICLE SIZE ANALYSIS; POLYETHYLENE GLYCOLS; VISCOSITY;

SHEAR MIXER;

POWDERS;

CALCIUM CARBONATE; DURCAL 5; ESKAL 500; MACROGOL; MACROGOL 20000; MACROGOL 3000; STURCAL F; UNCLASSIFIED DRUG;

AGGLOMERATION; APPARATUS; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DENSITY; GROWTH; LIQUID; MIXING; MORPHOLOGY; PARTICLE SIZE; PHYSICAL PHENOMENA; POROSITY; POWDER; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SHEAR RATE; SURFACE PROPERTY; VISCOSITY;

CALCIUM CARBONATE; CHEMISTRY, PHYSICAL; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POROSITY; POWDERS;

EID: 0034904044     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(01)00164-6     Document Type: Article

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