Effects of adenosine administration on spike-wave discharge frequency in genetically epileptic rats

Clinical and Experimental Pharmacology and Physiology

Volumn 28, Issue 8, 2001, Pages 643-646

  Ilbay, Gul ^a   Sahin, Deniz ^a   Karson, Ayse ^a   Ates, Nurbay ^a  

^a KOCAELI UNIVERSITY   (Turkey)

Author keywords

Absence seizure; Adenosine; Spike wave discharges; WAG Rij rats

Indexed keywords

ADENOSINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; BLOOD PRESSURE; BODY TEMPERATURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ELECTROENCEPHALOGRAM; EPILEPTIC DISCHARGE; FACILITATION; INJECTION; MALE; NERVE CONDUCTION; NONHUMAN; RAT; RAT STRAIN; RECTUM TEMPERATURE; SEIZURE; SENSORY NERVE; SPIKE WAVE;

ADENOSINE; ANIMALS; DISEASE MODELS, ANIMAL; ELECTROENCEPHALOGRAPHY; EPILEPSY; MALE; RATS;

EID: 0034903940     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.2001.03499.x     Document Type: Article

References (21)

1. The physiological role of adenosine in the central nervous system
2. Adenosine and neuroprotection
3. Levels of endogenous adenosine in rat striatum. I. Regulation by ionotropic glutamate receptors, nitric oxide and free radicals
4. Possible mechanisms underlying hyperexcitability in the epileptic mutant mouse tottering
5. Emerging insights into mechanisms of epilepsy: Implications for new antiepileptic drug development
6. Effect of adenosine receptor modulation on pentylenetetrazole-induced seizures in rats
7. Effect of intraperitoneal and intrahippocampal (CA1) 2-chloroadenosine in amygdaloid kindled rats
8. Cardiovascular effects of intracerebroventricular bicuculine in rats with absence seizures
9. Evidence for a critical role of GABAerjic transmission within the thalamus in the genesis and control of absence seizures in the rat
10. A receptor impairment in the genetic absence epilepsy rats from Strasbourg (GAERS): An immunocytochemical and receptor binding autoradiographic study
11. Genetic models of absence epilepsy, with emphasis on the WAG/Rij strain of rats
12. The effects of chronic treatment with calcium channel antagonist on two types of generalized epilepsies in rats
13. Effects of loreclezole on epileptic activity and on EEG and behaviour in rats with absence seizures
14. Protective effect of adenosine and nicotinamide against audiogenic seizure
15. Chronic adenosine A1 receptor agonist and antagonist: Effect on receptor density and N-methyl-D-aspartate induced seizure in mice
16. Sedative and anticonvulsant effects of adenosine analogs in mouse and rat
17. Is adenosine an endogenous anticonvulsant?
18. Adenosine receptors and behavioural actions of methylxanthines
19. Cerebrovascular responses to penthylenetetrazole: Time and dose dependent effects
20. Effect of penthylentetrazole-induced seizures on A1 adenosine receptor regional density in the mouse brains: A quantitative autoradiographic study
21. Status epilepticus may be caused by loss of adenosine anticonvulsant mechanisms