Chiral separations using ultrafiltration with a stereoselective binding agent

Separation Science and Technology

Volumn 36, Issue 7, 2001, Pages 1575-1594

  Romero, Jonathan ^a   Zydney, Andrew L ^a  

^a Institute University of Delaware Newark   (United States)

Author keywords

Chiral separations; Diafiltration; Membrane filtration; Stereoselective binding; Ultrafiltration

Indexed keywords

AMINO ACIDS; COMPUTER SIMULATION; ISOMERS; SOLUTIONS;

PURIFICATION FACTORS;

ULTRAFILTRATION;

AMINO ACID; BOVINE SERUM ALBUMIN; TRYPTOPHAN;

FILTRATION; MEMBRANE; SEPARATION;

ARTICLE; CALCULATION; CHIRALITY; MEMBRANE BINDING; MEMBRANE FILTER; PURIFICATION; STEREOCHEMISTRY; STEREOSPECIFICITY; THEORY; ULTRAFILTRATION;

EID: 0034900270     PISSN: 01496395     EISSN: None     Source Type: Journal    
DOI: 10.1081/SS-100103889     Document Type: Article

References (28)

1. Stereochemistry, a basis for sophisticated non-sense in pharmacokinetics and clinical pharmacology
2. Drug chirality: Impact on pharmaceutical regulation
3. Racemic mixtures and single stereoisomers: Industrial concerns and issues in drug development
4. Direct liquid chromatographic separation of enantiomers on immobilized protein stationary phases: III. Optical resolution of a series of N-aroyl D, L-amino acids by high-performance liquid chromatography on bovine serum albumin covalently bound to silica
5. Direct liquid chromatographic separation of enantiomers on immobilized protein stationary phases: IV. Molecular interaction forces and retention behavior in chromatography on bovine serum albumin as a stationary phase
6. Direct resolution of enantiomers by liquid affinity chromatography on albumin-agarose under isocratic conditions
7. Liquid chromatographic studies of the effect of temperature on the chiral recognition of tryptophan by silica-immobilized bovine albumin
8. Chromatographic properties of chemically bonded bovine serum albumin working as a chiral selector in alkaline mobile phases
9. Optical resolution of N-benzyl-cis-2-aminocyclohexanecaroxylic acid by preferential crystallization
10. Diels-alder cycloadditions of sulfonyl cyanides with cyclopentadiene. Synthesis of 2-azabicyclo[2.2.1]hepta-2,5-dienes
11. Diels-alder reactions of methanesulfonyl cyanide with cyclopentadiene. Industrial synthesis of 2-azabicyclo[2.2.1]hepta-5-en-3-one
12. Liquid membrane technology for the separation of racemic mixtures
13. Supported liquid membranes for the enantioselective transport of amino acid mediated by chiral crown ether - Effect of membrane solvent on transport rate and membrane stability
14. Optical resolution of an amino acid by an enantioselective ultrafiltration membrane
15. Ultrafiltration affinity purification
16. Surface modified polysulfone membranes: Separation of mixed proteins and optical resolution of tryptophan
17. Optical resolution of amino acids by ultrafilitration membranes containing serum albumin
18. Effect of surfactant agents and lipids on optical resolution of amino acids by ultrafiltration membranes containing bovine serum albumin
19. Resolution of enantiomers using enantioselective micelles in ultrafiltration systems
20. Enantiomeric separation of tryptophan by ultrafiltration using the BSA solution system
21. Enantiomeric separation by ultrafiltration: Complexation mechanism of tryptophan analogs to bovine serum albumin
22. The specific binding of L-tryptophan to serum albumin
23. Structural studies and organic ligand-binding properties of bovine plasma albumin
24. Molecular aspects of ligand binding to serum albumin
25. Membrane ultrafiltration: The diafiltration technique and its application to microsolute exchange and binding phenomena
26. Binding of bromosulphthalein sodium by human serum albumin using a continuous diafiltration technique
27. Optimization diagram for membrane separations