The development of highly efficient onium-type peptide coupling reagents based upon rational molecular design

Journal of Peptide Research

Volumn 58, Issue 2, 2001, Pages 129-139

  Li, P ^a   Xu, J C ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Coupling reagent; Molecular design; Peptide; Racemization; Reactivity

Indexed keywords

(1H 7 AZABENZOTRIAZOL 1 YLOXY)TRIS(PYRROLIDINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE; (1H AZABENZOTRIAZOL 1 YLOXY)TRIS(DIMETHYLAMINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE; (1H BENZOTRIAZOL 1 YLOXY)TRIS(DIMETHYLAMINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE; 1 (1 PYRROLIDINYL 1H 1,2,3 TRIAZOLO[4,5 B]PYRIDIN 1 YLMETHYLENE)PYRROLIDINIUM; 1 (1H BENZOTRIAZOL 1 YLOXY)PHENYLMETHYLENE PYRROLIDINIUM HEXACHLOROANTIMONATE; 1 HYDROXY 7 AZABENZOTRIAZOLE; 1 HYDROXYBENZOTRIAZOLE; 1,1,3,3 BIS(TETRAMETHYLENE)FLUORURONIUM HEXAFLUOROPHOSPHATE; 2 BROMO 1 ETHYLPYRIDINIUM HEXACHLOROANTIMONATE; 2 BROMO 1 ETHYLPYRIDINIUM TETRAFLUOROBORATE; 2 BROMO 3 ETHYL 4 METHYLTHIAZOLIUM TETRAFLUOROBORATE; 2 CHLORO 1,3 DIMETHYL 1H BENZIMIDAZOLIUM HEXAFLUOROPHOSPHATE; 2 FLUORO 1 ETHYLPYRIDINIUM HEXACHLOROANTIMONATE; 2 FLUORO 1 ETHYLPYRIDINIUM TETRAFLUOROBORATE; 3 HYDROXY 3,4 DIHYDRO 4 OXO 1,2,3 BENZOTRIAZINE; 5 (1H 7 AZA BENZOTRIAZOL 1 YLOXY) 3,4 DIHYDRO 1 METHYL 2H PYRROLIUM HEXACHLOROANTIMONATE; 5 (1H BENZOTRIAZOL 1 YL) 3,4 DIHYDRO 1 METHYL 2H PYRROLIUM HEXACHLOROANTIMONATE N OXIDE; CATION; CHLORO(4 MORPHOLINO)METHYLENEMORPHOLINIUM HEXAFLUOROPHOSPHATE; CYCLOSPORIN O; DOLOSTATIN 15; LEUCINE ENKEPHALIN; N (1H BENZOTRIAZOL 1 YLMETHYLENE) N METHYLMETHANAMINIUM HEXACHLOROANTIMONATE N OXIDE; N [(1H BENZOTRIAZOL 1 YL)(DIMETHYLAMINO)METHYLENE] N METHYLMETHANAMINIUM HEXAFLUOROPHOSPHATE N OXIDE; N HYDROXYSUCCINIMIDE; N,N' BIS(2 OXO 3 OXAZOLIDINYL)PHOSPHINIC CHLORIDE; O (1H BENZOTRIAZOL 1 YL) N,N,N',N BIS(TETRAMETHYLENE)URONIUM HEXAFLUOROPHOSPHATE; PEPTIDE; REAGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CHEMOREACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MODEL; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; RACEMIC MIXTURE; STRUCTURE ACTIVITY RELATION;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG DESIGN; ISOMERISM; MOLECULAR STRUCTURE; OLIGOPEPTIDES; ONIUM COMPOUNDS; PEPTIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034899582     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3011.2001.00867.x     Document Type: Article

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