The clinical relevance of the citrate effect on International Normalized Ratio determinations depends on the reagent and instrument combination used

Blood Coagulation and Fibrinolysis

Volumn 12, Issue 5, 2001, Pages 399-404

  Lottin, L ^a   Woodhams, Barry J ^b   Saureau, M C ^a   Robert, A ^c   Aillaud, M F ^d   Arnaud, E ^a   Martinoli, J L ^a  

^a Diagnostica Stago ^*  (France)

^b Serbio Diagnostica Stago   (France)

^c HÔPITAL SAINT ANTOINE   (France)

^d TIMONE HOSPITAL   (France)

Author keywords

Anticoagulant concentration; Citrate; Prothrombin time assays; Thromboplastin reagents

Indexed keywords

CITRIC ACID; THROMBOPLASTIN;

ANTICOAGULANT THERAPY; ARTICLE; DIAGNOSTIC ACCURACY; HEMOSTASIS; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTHROMBIN TIME; STANDARDIZATION;

ANIMALS; BLOOD COAGULATION TESTS; CITRIC ACID; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INDICATORS AND REAGENTS; INTERNATIONAL NORMALIZED RATIO; RABBITS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; THROMBOPLASTIN;

EID: 0034897663     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001721-200107000-00010     Document Type: Article

References (10)

1. rd Report
2. Assessment of the influence of citrate concentration on the international normalized ratio (INR) determined with 12 reagent-instrument combinations
3. Effect of concentration of trisodium citrate anticoagulant on calculation of the international normalized ratio and the international sensitivity index of thromboplastins
4. Effect of 3.2% vs 3.8% sodium citrate concentration on routine coagulation testing
5. Guidelines for thromboplastin and plasmas used to control oral anticoagulant therapy. 48th Report
6. A comparison of two sodium citrate concentrations in two evacuated blood collection systems for prothrombin time and ISI determination
7. Les causes d'erreurs dans les tests d'exploration de la coagulation sanguine emploi d'un Bain-Marie électro-magnétique
8. An evaluation of a simple manual clotting method as an alternative to the tilttube method
9. A study of the variability seen in the INR obtained using different sensitivity thromboplastin reagents on different instrument types