Role of endothelin-1 receptors in healthy anaesthetized rabbits

Clinical and Experimental Pharmacology and Physiology

Volumn 28, Issue 8, 2001, Pages 647-650

  Schmitz Spanke, S ^a   Schipke, J D ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Cardiac function; Circulatory system; Endothelin; Endothelin receptors; Inotropism; Rabbit; Vasomotion

Indexed keywords

2 [[2 [[2 [[(HEXAHYDRO 1H AZEPIN 1 YL)CARBONYL]AMINO] 4 METHYLPENTANOYL]AMINO] 3 (1 METHYL 1H INDOL 3 YL)PROPIONYL]AMINO] 3 (2 PYRIDYL)PROPIONIC ACID; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; HEART EJECTION FRACTION; HEART FUNCTION; HEART LEFT VENTRICLE PRESSURE; INOTROPISM; NONHUMAN; PROTEIN DETERMINATION; RECEPTOR BLOCKING; RECEPTOR INTRINSIC ACTIVITY; SYSTOLE; VASCULAR RESISTANCE; VASOCONSTRICTION; VASOMOTOR REFLEX;

ANESTHESIA; ANIMALS; AZEPINES; DRUG INTERACTIONS; ENDOTHELIN-1; HEART RATE; INDOLES; RABBITS; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN; VASOMOTOR SYSTEM;

EID: 0034897512     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.2001.03500.x     Document Type: Article

References (29)

1. Potential physiological and pathological significance of endothelins
2. Potential role of endothelin-1 and endothelin antagonists in cardiovascular diseases
3. Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice
4. Role of endogenous endothelin in chronic heart failure: Effect of long-term treatment with an endothelin antagonist on survival, hemodynamics, and cardiac remodeling
5. The relationship between serum nitrate and endothelin-1 concentrations in preeclampsia
6. Endothelin-1 from prostate cancer cells is enhanced by bone contact which blocks osteoclastic bone resorption
7. Effect of cold exposure, exercise and high altitude on plasma endothelin-1 and endothelial cell markers in man
8. Therapeutic potential of endothelin receptor antagonists in diabetes
9. A computer program to acquire and process data from the experimental laboratory
10. REGM: A multivariate general linear hypothesis program
11. A receptor antagonist
12. Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ 788
13. Hemodynamic effects of endothelin in conscious rats
14. Effects of intravenous endothelin on hemodynamics and cardia contractility in conscious Milan normotensive rats
15. Effect of endothelin on total and regional coronary resistance and on myocardial contractility
16. Effect of endothelin-1 and its combination with adenosine on myocardial contractility and myocardial energy metabolism in vivo
17. Positive inotropic and vasoconstrictive effects of endothelin-1 in in vivo and in vitro experiments: Characteristics and the role of L-type calcium channels
18. Endothelin-1 causes a biphasic response in systemic vasculature and increases myocardial contractility in conscious rabbits
19. Modulation of systolic and diastolic function by endothelin-1: Relation to coronary flow
20. Positive chronotropic effects of endothelin, a novel endothelium-derived vasoconstrictor peptide
21. Endothelin receptors in the failing and nonfailing human heart
22. Contrasting inotropic effects of endogenous endothelin in the normal and failing human heart: Studies with an intracoronary ET(A) receptor antagonist
23. Inotropic effects of endothelin-1: Interaction with molsidomine and with BQ 610
24. Subcellular mechanisms of endothelin action in vascular system
25. 1-adrenergic stimulated phosphatidylinositol cycle in cultured rat cardiomyocytes
26. + exchanger
27. Heterogeneity and underlying mechanism for inotropic action of endothelin-1 in rat ventricular myocytes
28. ++ sensitivity in normal and stunned myocardium of isolated rabbit hearts
29. Nonuniform course of left ventricular pressure fall and its regulation by load and contractile state