EGTA treatment of human airways in vitro unmasks M1/MUC5AC mucin in submucosal glands

European Respiratory Journal

Volumn 18, Issue 1, 2001, Pages 176-183

  Roger, P ^a   Gascard, J P ^a   Bara, J ^a   Dulmet, E ^a   Brink, C ^a  

^a CENTRE CHIRURGICAL MARIE LANNELONGUE   (France)

Author keywords

EGTA; Glands; Goblet cells; Human airways; M1 MUC5AC mucin

Indexed keywords

CALCIUM CHELATING AGENT; EGTAZIC ACID; EPITOPE; LACTATE DEHYDROGENASE; MONOCLONAL ANTIBODY; MUCIN; PROTEIN;

ACCURACY; AIRWAY; ARTICLE; BRONCHUS; BRONCHUS MUCOSA; BRONCHUS SECRETION; CELL LABELING; CONTROLLED STUDY; ENZYME ACTIVITY; EPITHELIUM CELL; EVALUATION; EXOCRINE GLAND; GOBLET CELL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNORADIOMETRIC ASSAY; IN VITRO STUDY; MASKING; MEASUREMENT; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN SECRETION; STAINING; SUBMUCOSA;

BRONCHI; EGTAZIC ACID; HUMANS; LUNG NEOPLASMS; MUCINS; RESPIRATORY MUCOSA; SENSITIVITY AND SPECIFICITY;

EID: 0034895344     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.01.00105301     Document Type: Article

References (26)

1. Effect of calcium on sulfated mucous glycoprotein secretion in dog trachea
2. Extracellular calcium ion depletion induces release of glycoproteins by canine trachea
3. Effect of floating a gel matrix on mucin release in cultured airway epithelial cells
4. The effects of calcium and calcium ionophore A23187 on mucin secretion and potential difference in the isolated chicken trachea
5. Differential effects of calcium ions on glycoconjugate secretion by canine tracheal explants
6. 2+ effect on stimulation of mucin secretion form chicken trachea in vitro
7. 2+ effect on stimulation of common mucins and unique sulfate-rich components from chicken trachea in vitro
8. Effects of calcium on intestinal mucin: Implications for cystic fibrosis
9. Monoclonal antibodies against oncofetal mucin M1 antigens associated with precancerous colonic mucosae
10. Oncofetal mucin M1 epitope family: Characterization and expression during colonic carcinogenesis
11. Gastric M1 mucin, an early oncofetal marker of colon carcinogenesis, is encoded by the MUC5AC gene
12. M1/MUC5AC mucin released by human airways in vitro
13. Development of a functional human bronchial model of mucin secretion
14. ATP induced MUC5AC release from human airways in vitro
15. Aneuploidy and expression of gastric-associated mucus antigens M1 and CEA in colorectal adenomas
16. Immunochemical characterization of mucins: Polypeptides (MI) and polysaccharide (A and Lewis) antigens
17. Protein measurement with the Folin Phenol reagent
18. A fucose residue can mask the MUC-1 epitopes in normal and cancerous gastric mucosae
19. MUC5AC, but not MUC2, is a prominent mucin in respiratory secretions
20. Developmental expression of mucin genes in the human respiratory tract
21. MUC5B and MUC7 are differentially expressed in mucous and serous cells of submucosal glands in human bronchial airways
22. Developmental mucin gene expression in the human respiratory tract
23. Expression of human mucin genes in respiratory, digestive and reproductive tracts ascertained by in situ hybridization
24. Relating mucous, calcium and sweat in a new concept of cystic fibrosis
25. A fine structural study of divalent cation-mediated epithelial union with connective tissue in human oral mucosa
26. EDTA-mediated separation of cat tracheal lining epithelium