Higher than normal plasma interleukin-6 concentrations in cancer patients with depression: Preliminary findings

American Journal of Psychiatry

Volumn 158, Issue 8, 2001, Pages 1252-1257

  Musselman, D L ^a   Miller, A H ^a   Porter, M R ^a   Manatunga, A ^a   Gao, F ^a   Penna, S ^a   Pearce, B D ^a   Landry, J ^a   Glover, S ^a   McDaniel, J S ^a   Nemeroff, C B ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; HYDROCORTISONE; INTERLEUKIN 6;

ADULT; AGED; ARTICLE; BLOOD LEVEL; BREAST CANCER; CANCER; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; CYTOKINE RELEASE; DEPRESSION; DEXAMETHASONE SUPPRESSION TEST; DIAGNOSTIC PROCEDURE; DISEASE SEVERITY; ESOPHAGUS CANCER; FEMALE; HAMILTON SCALE; HUMAN; HYDROCORTISONE BLOOD LEVEL; ILLNESS BEHAVIOR; IMMUNOPATHOLOGY; MALE; PANCREAS CANCER; PATHOPHYSIOLOGY; PRELIMINARY COMMUNICATION; PRIORITY JOURNAL;

ADULT; ANALYSIS OF VARIANCE; COMORBIDITY; DEPRESSIVE DISORDER; DEXAMETHASONE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; HYDROCORTISONE; INTERLEUKIN-6; MALE; MIDDLE AGED; NEOPLASMS; PSYCHIATRIC STATUS RATING SCALES;

EID: 0034893542     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/appi.ajp.158.8.1252     Document Type: Article

References (44)

1. Depression in the cancer patient: A commentary on diagnosis, biology, and treatment
2. Quality of life in treated head and neck cancer patients: A preliminary report
3. Depression and anxiety in patients undergoing diagnostic investigations for head and neck cancers
4. Depression and tumor stage in cancer of the head and neck
5. Comparison of psychiatric symptoms in carcinoma of the pancreas with those in some other intra-abdominal neoplasms
6. Comparative psychological disturbance in patients with pancreatic and gastric cancer
7. Depression and carcinoma of the pancreas
8. Psychological distress and depression
9. Biological and clinical aspects of interleukin-6
10. Acute-phase proteins and other systemic responses to inflammation
11. Neuroendocrine-immune interactions
12. A molecular basis for bidirectional communication between the immune and neuroendocrine systems
13. Immune-neuro-endocrine interactions: Facts and hypotheses
14. Sickness behavior as a new target for drug development
15. Endotoxin produces a depressive-like episode in rats
16. Interleukin-6 and the acute phase response
17. Psychopathology of pancreatic cancer: A psychobiologic probe
18. Indicators of immune activation in major depression
19. Elevated plasma concentrations of alpha 1-acid glycoprotein, a putative endogenous inhibitor of the tritiated imipramine binding site, in depressed patients
20. Expression of tumor necrosis factor alpha (TNF alpha) and interleukin 6 (IL-6) mRNA in adult human astrocytes: Comparison with adult microglia and fetal astrocytes
21. Expression of interleukin (IL)-1 beta, IL6 and their respective receptors in the normal rat brain and after injury
22. Differential expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) messenger RNAs in rat hypothalamus
23. Cellular localization of interleukin 6 mRNA and interleukin 6 receptor mRNA in rat brain
24. Localization of interleukin 6 mRNA and interleukin 6 receptor mRNA in rat brain
25. In vitro production of IL-6, IL-1b, and tumor necrosis factor-alpha by human embryonic microglial and neural cells
26. "Mini-Mental State": A practical method for grading the cognitive state of patients for the clinician
27. A rating scale for depression
28. The Carroll rating scale for depression, I: Development, reliability and validation
29. Psychiatric diagnosis: Are clinicians still necessary?
30. The dexamethasone suppression test for melancholia
31. The dexamethasone suppression test in depression
32. The dexamethasone suppression test for diagnosis and prognosis in psychiatry
33. APA task force on laboratory tests in psychiatry: The dexamethasone suppression test: An overview of its current status in psychiatry
34. Inferences about one or two populations: Ordinal data
35. Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression
36. Cytokine production and treatment response in major depressive disorder
37. Increased serum IL-6 and IL-1 receptor antagonist concentrations in major depression and treatment resistant depression
38. Interleukin-6-(IL-6) plasma levels in depression and schizophrenia: Comparison between the acute state and after remission
39. The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation
40. Biology of mood disorders
41. Depression in women treated for gynecological cancer: Clinical and neuroendocrine assessment
42. The proinflammatory cytokine, interleukin-1 alpha, reduces glucocorticoid receptor translocation and function
43. Relationships between interleukin-6 activity, acute phase proteins, and function of the hypothalamic-pituitary-adrenal axis in severe depression