Effects of Tripterygium wilfordii saponins and interleukin-10 on dendritic cells from human peripheral blood

Acta Pharmacologica Sinica

Volumn 22, Issue 8, 2001, Pages 721-724

  Wang, S J ^a   Yao, K ^a   Xie, F Y ^a   Ji, X H ^a  

^a Zhenjiang Medical College   (China)

Author keywords

CD80 antigens; Cell culture; Dendritic cells; Enzyme linked immunoabsorbent assay; Flow cytometry; HLA DR antigens; Interleukin 10; Interleukin 12; Reverse transcriptase polymerase chain reaction; Tripterygium wilfordii

Indexed keywords

B7 ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; SAPONIN; TRIPTERYGIUM WILFORDII EXTRACT; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BLOOD; CHINESE MEDICINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOSUPPRESSIVE TREATMENT; NORMAL HUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANTIGENS, CD80; CELL SEPARATION; CELLS, CULTURED; DENDRITIC CELLS; FLOW CYTOMETRY; HLA-DR ANTIGENS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTERLEUKIN-10; LEUKOCYTES, MONONUCLEAR; SAPONINS; TRIPTERYGIUM;

EID: 0034891550     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Triptolide inhibits the activity of NF-κB in human T lymphocyte
2. Triptergium wilfordii saponins and interleukin-10 prevent induction of experimental autoimmune thyroiditis by dendritic cells
3. Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo
4. IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells
5. Interleukin-10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via down-regulation of class II major histocompatibility complex expression
6. Dendritic cells and the control of immunity
7. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation
8. Bacterial lipopolysaccharide stimulates the production of cytokines and the expression of costimulatory molecules by human peripheral blood dendritic cells: Evidence for a soluble CD14-dependent pathway
9. The cytokine profile expressed by human dendritic cells is dependent on cell subtype and mode of activation
10. Differential T cell costimulatory requirements on CD28-deficient mice
11. Interferon-γ and IL-10 inhibit antigen presentation by Langerhans cells for T helper type I cells by suppressing their CD80 expression
12. Interleukin-10 differentially regulates B7-1 (CD80) and B7-2 (CD86) expression on human peripheral blood cells
13. + T cells
14. Dendritic cells, but not macrophages, produce IL-12 immediately following Leishmania donovani infection
15. Normal B cells fail to secrete interleukin-12