The effect of formulation and concentration of cholesteryl butyrate solid lipid nanospheres (SLN) on NIH-H460 cell proliferation

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 52, Issue 2, 2001, Pages 197-202

  Ugazio, Elena ^a   Marengo, Emilio ^b   Pellizzaro, Cinzia ^c   Coradini, Danila ^c   Peira, Elena ^a   Daidone, Maria Grazia ^c   Gasco, Maria Rosa ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^c NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Cholesteryl butyrate; Colloidal systems; Factorial design; NIH H460 cell proliferation; Solid lipid nanospheres

Indexed keywords

ANTIMITOTIC AGENT; BUTANOL; BUTYRIC ACID; CHOLESTEROL BUTYRATE; CHOLESTEROL DERIVATIVE; EPIKURON 200; NANOPARTICLE; PHOSPHATIDYLCHOLINE; SOLID LIPID NANOPARTICLE; TAUROCHOLIC ACID; UNCLASSIFIED DRUG; WATER;

ARTICLE; CELL CULTURE; CELL PROLIFERATION; COLLOID; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG FORMULATION; FACTORIAL ANALYSIS; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; MICROEMULSION;

BUTYRIC ACID; CAPSULES; CELL DIVISION; CHEMISTRY, PHARMACEUTICAL; CHOLESTEROL ESTERS; EMULSIONS; HISTAMINE ANTAGONISTS; HUMANS; LIPOSOMES; TUMOR CELLS, CULTURED;

EID: 0034885601     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(01)00176-X     Document Type: Article

References (24)

1. Suppression of growth of hepatocellular carcinoma by sodium butyrate in vitro and in vivo
2. Effect of sodium butyrate on human breast cancer cell lines
3. Cellular growth state differentially regulated enterocyte gene expression ion butyrate-treated HT29 cells
4. Sodium butyrate inhibits c-myc splicing and interferes with signal transduction in ovarian carcinoma cells
5. In vivo crypt surface hyperproliferation is decreased by butyrate and increased by deoxycholate in normal rat colon: associated in vivo effects on c-fos and c-jun expression
6. Butyrate modulates DNA-damage-induced p53 response by induction of p53-independent differentiation and apoptosis
7. Bcl-2 expression regulates sodium butyrate-induced apoptosis in human breast cancer cells
8. Plasma pharmacokinetics of butyrate after intravenous administration of sodium butyrate or oral administration of tributyrin or sodium butyrate to mice and rats
9. Clinical pharmacology of sodium butyrate in patients with acute leukaemia
10. Cholesteryl butyrate in solid lipid nanospheres as an alternative approach for butyric acid delivery
11. Optimization of incorporation of deoxycorticosterone acetate in lipospheres
12. Sterilization and freeze-drying of drug-free and drug-loaded solid lipid nanoparticles
13. Determination of free, total, and esterified cholesterol by high-performance liquid chromatography
14. Establishment and identification of small cell lung cancer lines having classic and variant features
15. A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity
16. Long-acting injectable oxytetracycline-lipospheres formulations
17. Submicron-sized parenteral carrier systems based on solid lipids
18. Solid lipid nanoparticles (SLN). An alternative colloidal carrier system for controlled drug delivery
19. Solid lipid nanoparticles (SLN) for intravenous delivery
20. Correlation between long-term stability of solid lipid nanoparticles (SLN) and crystallinity of the lipid phase
21. Enzymatic degradation of SLN-effect of surfactant and surfactant mixtures