Lack of effect of furfural on unscheduled DNA synthesis in the in vivo rat and mouse hepatocyte DNA repair assays and in precision-cut human liver slices

Food and Chemical Toxicology

Volumn 39, Issue 10, 2001, Pages 999-1011

  Lake, B G ^a   Edwards, A J ^a   Price, R J ^a   Phillips, B J ^a   Renwick, A B ^a   Beamand, J A ^a   Adams, T B ^b  

^a TNO BIBRA International Ltd   (United Kingdom)

^b Federal Emergency Management Agency   (United States)

Author keywords

Furfural; Human liver; In vivo DNA repair; Mouse hepatocytes; Precision cut liver slices; Rat hepatocytes; Unscheduled DNA synthesis

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; AFLATOXIN B1; AMINOAZOTOLUENE; DIMETHYLNITROSAMINE; FURFURAL; N (2 FLUORENYL)ACETAMIDE; THYMIDINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSAY; AUTORADIOGRAPHY; CONTROLLED STUDY; CYTOTOXICITY; DNA REPAIR; DOSE RESPONSE; FEMALE; GENOTOXICITY; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL; LIVER PERFUSION; MALE; MAXIMUM TOLERATED DOSE; MOUSE; NONHUMAN; RAT; UNSCHEDULED DNA SYNTHESIS;

2-ACETYLAMINOFLUORENE; ANIMALS; CARCINOGENS; CELLS, CULTURED; DIMETHYLNITROSAMINE; DNA; DNA REPAIR; DNA REPLICATION; FEMALE; FURALDEHYDE; HEPATOCYTES; HUMANS; LIVER; MALE; MICE; MICE, INBRED STRAINS; O-AMINOAZOTOLUENE; RATS; RATS, INBRED F344;

EID: 0034885573     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(01)00050-3     Document Type: Article

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