Protective effects of a protein-bound polysaccharide, PSK, on Candida albicans infection in mice via tumor necrosis factor-α induction

International Immunopharmacology

Volumn 1, Issue 9-10, 2001, Pages 1797-1811

  Ohmura, Yoshio ^a   Matsunaga, Kenichi ^a   Motokawa, Isamu ^a   Sakurai, Katsuo ^a   Ando, Takao ^a  

^a KUREHA CORPORATION   (Japan)

Author keywords

Anti infectious effects of BRM; Candida albicans; Induction of tumor necrosis factor ; Protein bound polysaccharide

Indexed keywords

1,3 BETA GLUCANASE; AMINOGUANIDINE; AMPHOTERICIN B; BETA 1,3 GLUCAN; CARRAGEENAN; CYCLOPHOSPHAMIDE; HYDRAZINE; KRESTIN; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANDIDA ALBICANS; CANDIDIASIS; CELL FUNCTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG HYDROLYSIS; DRUG MECHANISM; FEMALE; GENE EXPRESSION; INFECTION PREVENTION; INOCULATION; LEUKOCYTE; MOLECULE; MOUSE; MYCOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INDUCTION; PROTEIN STRUCTURE; SPLEEN; SURVIVAL RATE; SURVIVAL TIME;

ANIMALS; BIOLOGICAL RESPONSE MODIFIERS; CANDIDA ALBICANS; CANDIDIASIS; ENDOTOXINS; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXUDATES AND TRANSUDATES; FEMALE; INDICATORS AND REAGENTS; LEUKOPENIA; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NITRIC OXIDE SYNTHASE; PHAGOCYTOSIS; POLYSACCHARIDES; PROTEOGLYCANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPLEEN; SUPEROXIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034885250     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1567-5769(01)00104-7     Document Type: Article

References (55)

1. Epidemiology of nosocomial fungal infections, with emphasis to Candida species
2. Mechanisms of resistance to fungal infections
3. Colony-stimulating factors: Clinical applications
4. Trends in immunotherapy of fungal infections
5. Anti-metastatic effects of PSK (Krestin), a protein-bound polysaccharide obtained from basidiomycetes, an overview
6. Efficacy of immunochemotherapy as adjuvant treatment after curative resection of gastric cancer
7. Randomized controlled study on adjuvant immunochemotherapy with PSK in curatively resected colorectal cancer
8. Krestin (PSK)
9. Protective effect of PSK, a protein-bound polysaccharide preparation against candidiasis in tumor-bearing mice
10. The effect of a protein-bound polysaccharide from Coriolus versicolor on immunological parameters and experimental infection in mice
11. Protective effect of biological response modifiers on murine cytomegalovirus infection
12. Influence of PSK (Krestin) on resistance to infection of Pseudomonas aeruginosa in tumor-bearing mice
13. Immunotherapy of patients with multiple organ failure (MOF)
14. Effect of PSK on recurrent genital herpes
15. In vitro inactivation of herpes simplex virus by a biological response modifier, PSK
16. Nitric oxide production does not directly increase macrophage candicidal activity
17. Antitumor activity of carboxymethylglucans obtained by carboxymethylation of β (1-3)-D-glucan from Alcaligenes faecalis var. Myxogenes IFO 13140
18. Evidence that tumor necrosis factor has an important role in antibacterial resistance
19. Hydrazinolysis of asparagines-linked sugar chain to produce free oligosaccharide
20. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction
21. Increased susceptibility of TNF-α lymphotoxin-α double knockout mice to systemic candidiasis through impaired recruitment of neutrophils and phagocytosis of Candida albicans
22. Plasma (1 → 3)-β-D-glucan measurement in diagnosis of invasive deep mycosis and fungal febrile episode
23. Protective effects of various BRMs against Candida albicans infection in mice
24. Protective effect of oral administration of several traditional Kampo-medicines on lethal Candida infection in immunosuppressed mice
25. Effects of BCG, Corynebacterium parvum, and methanol-extraction residue in the reduction of mortality from Staphylococcus aureus and Candida albicans infection in immunosuppressed mice
26. Protective effect of OK-432 (a streptococcal preparation) on experimental candidiasis
27. Repression of the capacity to produce tumor necrosis factor alpha in Candida albicans-infected mice and reversal of the repression by oral Juzen-taiho-to treatment
28. Protective effect of recombinant human granulocyte colony stimulating factor (rG-CSF) against various microbial infections in neutropenic mice
29. Protective effect of glucan in experimentally induced candidiasis
30. Enhancement by ubenimex (Bestatin) of host resistance to Candida albicans infection
31. Protecting effect of chitin and chitosan on experimentally induced murine candidiasis
32. Mechamisms of host defense against Candida species: I. Phagocytosis by monocytes and monocyte-derived macrophages
33. Tumor necrosis factor and interleukin 6 in Candida albicans infection in normal and granulocytopenic mice
34. Tumor necrosis factor as an autocrine and paracrine signal controlling the macrophage secretory response to Candida albicans
35. Tumor necrosis factor alpha has a protective role in a murine model of systemic candidiasis
36. Production and function of cytokines in natural and acquired immunity to Candida albicans infection
37. TNF receptors in murine Candida albicans infection: Evidence for an important role of TNF receptor p55 in antifungal defense
38. In vitro production of tumor necrosis factor by murine splenic macrophages stimulated with mannoprotein constituents of Candida albicans cell wall
39. Balance of inflammatory cytokines related to severity and mortality of murine sepsis
40. Priming effect of interferons and interleukin 2 on endogenous production of tumor necrosis factor in mice
41. Contribution of cytokines on suppression of lung metastasis
42. Interleukin-6/interferon-β2 as a circulating hormone: Induction by cytokine administration in man
43. The β-glucan binding lectin site of mouse CR3 (CD11b/CD18) and its function in generating a primed state of the receptor that mediates cytotoxic activation in response to iC3b-opsonized target cells
44. A simplified representation of protein conformations for rapid simulation of protein folding
45. Direct action of a protein-bound polysaccharide, PSK, on transforming growth factor-β
46. Susceptibility of natural killer (NK) cells to reactive oxygen species (ROS) and their restoration by the mimics of superoxide dismutase (SOD)
47. C-C and C-X-C chemokine synthesis and release via receptors by human alveolar macrophages treated with three types of stimulants
48. + T-cell response in gut-associated lymphoid tissue (GALT) of specific pathogen-free mice
49. Significant prolongation of disease-free period gained by oral polysaccharide K (PSK) administration after curative surgical operation of colorectal cancer
50. Fate and distribution of an antitumor protein-bound polysaccharide PSK (Krestin)
51. Production of antiserum against antitumor protein-bound polysaccharide preparation, PSK (Krestin) and its pharmacologyical application
52. Restoration of antibody-forming capacities by PS-K in tumor-bearing mice
53. Alteration in frequency of interleukin-2 (IL-2)-, gamma interferon-, or IL-4-secreting splenocytes induced by Candida albicans mannan and/or monophosphoryl lipid A
54. Effectiveness of a vaccine composed of heat-killed Candida albicans and a novel adjuvant, LT (R192G), against systemic candidiasis