Extremely low doses of tissue factor pathway inhibitor decrease mortality in a rabbit model of septic shock

Intensive Care Medicine

Volumn 27, Issue 8, 2001, Pages 1274-1280

  Matyal, R ^a   Vin, Y ^a   Delude, R ^a   Lee, C ^a   Creasey, A ^b   Fink, M ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

^c Division of Crit Care Med   (United States)

Author keywords

Coagulation; Disseminated intravascular coagulation; Escherichia coli; Peritonitis; Tissue factor pathway inhibitor

Indexed keywords

GENTAMICIN; RECOMBINANT TISSUE FACTOR PATHWAY INHIBITOR;

ANIMAL MODEL; ARTICLE; BACTERIAL PERITONITIS; CONTROLLED STUDY; DRUG EFFICACY; ESCHERICHIA COLI; MORTALITY; NONHUMAN; RABBIT; SEPTIC SHOCK; SURVIVAL TIME; TREATMENT OUTCOME;

ANIMALS; ANTICOAGULANTS; DISSEMINATED INTRAVASCULAR COAGULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI INFECTIONS; FACTOR XA; LIPOPROTEINS; PERITONITIS; RABBITS; SHOCK, SEPTIC; STATISTICS, NONPARAMETRIC; SURVIVAL ANALYSIS; TIME FACTORS;

EID: 0034884867     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001340100992     Document Type: Article

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