Pharmacokinetic basis for oral perioperative prophylaxis with ofloxacin in general surgery

Infection

Volumn 29, Issue 4, 2001, Pages 222-227

  Schwarz, M ^a   Isenmann, R ^a   Weikert, E ^a   Ebeling, P ^a   Thomsen, J ^a   Beger, H G ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

Antibiotic; General surgery; Perioperative prophylaxis

Indexed keywords

METRONIDAZOLE; MEZLOCILLIN; OFLOXACIN;

AREA UNDER THE CURVE; ARTICLE; CHOLECYSTECTOMY; CLINICAL ARTICLE; COLON RESECTION; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG HALF LIFE; GENERAL SURGERY; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; GRAM POSITIVE COCCI; HERNIOPLASTY; HIGH RISK POPULATION; HUMAN; HUMAN TISSUE; INFECTION PREVENTION; INFECTION RISK; MINIMUM INHIBITORY CONCENTRATION; PANCREAS RESECTION; PERIOPERATIVE PERIOD; SURGICAL INFECTION; TISSUE DISTRIBUTION;

ADMINISTRATION, ORAL; ANTI-INFECTIVE AGENTS; ANTIBIOTIC PROPHYLAXIS; HUMANS; INJECTIONS, INTRAVENOUS; METRONIDAZOLE; MEZLOCILLIN; OFLOXACIN; PENICILLINS; PREOPERATIVE CARE; RISK FACTORS; TREATMENT OUTCOME;

EID: 0034882692     PISSN: 03008126     EISSN: None     Source Type: Journal    
DOI: 10.1007/s15010-001-1151-5     Document Type: Article

References (40)

1. Surgical wound infection rates by wound class, operative procedure, and patient risk index. National nosocomial infections surveillance system
2. The cost of infection in surgical patients: A case-control study
3. The timing of prophylactic administration of antibiotics and the risk of surgical-wound infection
4. Prophylaxis of postoperative infections
5. Antibiotic prophylaxis in visceral surgery
6. Single dose systemic antibiotic prophylaxis of surgical wound infections
7. Reducing the cost of surgical prophylaxis
8. Cost increase due to incorrect antibiotic prophylaxis in visceral, thoracic and vascular surgery
9. Prophylactic antibiotics in elective colorectal surgery
10. Comparison between systemic and oral antimicrobial prophylaxis in colorectal surgery
11. Oral neomycin and erythromycin compared with single-dose systemic metronidazole and ceftriaxone prophylaxis in elective colorectal surgery
12. Perioperative antibiotikaprophylaxe - Empfehlungen der Deutschen Gesellschaft für Krankenhaushygiene (DGKH)
13. Quality standard for antimicrobial prophylaxis in surgical procedures
14. A new fluorinated quinolone - Pharmakokinetits of ofloxacin
15. Value of oral antibiotic prophylaxis in colorectal surgery
16. Oral ciprofloxacin as prophylaxis in gastroduodenal surgery
17. Classification and identification of bacteria
18. The penetration of antibiotics into human pancreas
19. Antimicrobial prophylaxis in surgery
20. Antibiotic prophylaxis in surgical procedures. A critical analysis of the literature
21. The epidemiology of wound infection. A 10-year prospective study of 62,939 wounds
22. A five-year prospective study of 23,649 surgical wounds
23. Perioperative antibiotic prophylaxis for herniorrhaphy and breast surgery
24. A reevaluation of antibiotic prophylaxis in laparoscopic cholecystectomy
25. Is there an indication for general perioperative antibiotic prophylaxis in laparoscopic plastic hernia repair with implantation of alloplastic tissue?
26. Surgical wound infection
27. Identifying patients at high risk of surgical wound infection. A simple multivariate index of patient susceptibility and wound contamination
28. Detrimental effects of perioperative blood transfusion
29. Evaluating surgical risk: The importance of technical factors in determining outcome
30. Antimicrobial drug utilisation in hospitals in Italy and other European countries
31. Spectrum of bacteria in infections in abdominal surgery
32. Comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1993). I. Susceptibility distribution
33. Overview of the fluoroquinolone antibiotics
34. Risk factors for surgical-wound infection in general surgery: A prospective study
35. Preventing postoperative infections: Current treatment recommendations
36. Quinolone pharmacokinetics and metabolism
37. Comparative antimicrobial activity of lomefloxacin, norfloxacin, ofloxacin, ciprofloxacin and enoxacin against > 500 bacterial isolates
38. Pharmacokinetics and relative bioavailability of ofloxacin tablets in 12 healthy volunteers
39. Comparative pharmacokinetics of ofloxacin and ciprofloxacin