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Volumn 9, Issue 3, 2001, Pages 185-200

Liver organotropism and biotransformation of a novel platinum-ursodeoxycholate derivative, Bamet-UD2, with enhanced antitumour activity

(6) Larena, M G a Martinez Diez, M C a Monte, M J a Dominguez, M F a Pascual, M J a Marin, J J G a

a UNIVERSITY OF SALAMANCA (Spain)

Author keywords

Biotransformation; Chemotherapy; Glycocholic acid; Pharmacokinetics; Pt(II); Tumour

Indexed keywords

2 ETHOXY 1(2H) QUINOLINECARBOXYLIC ACID ETHYL ESTER; 3,3' DIAMINODIPROPYLAMINE; ACID ANHYDRIDE; ALANINE AMINOTRANSFERASE; ANTIVIRUS AGENT; ASPARTATE AMINOTRANSFERASE; BAMET D3; BAMET UD2; BILE ACID; CHLORIDE ION; CHOLIC ACID; CISPLATIN DERIVATIVE; CREATININE; CYTOSTATIC AGENT; DNA; GLUCOSE; GLYCINE; GLYCOCHOLIC ACID; HEMOGLOBIN; NEW DRUG; PLATINUM DERIVATIVE; POLYAMINE; POTASSIUM ION; SODIUM CHLORIDE; SODIUM DERIVATIVE; SODIUM ION; STEROID; UNCLASSIFIED DRUG; UNINDEXED DRUG; UREA; URSODEOXYCHOLIC ACID DERIVATIVE;

ANESTHESIA INDUCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; BILE; BIOTRANSFORMATION; CANCER TRANSPLANTATION; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; DRUG TRANSFORMATION; DRUG UPTAKE; FECES ANALYSIS; HEPATOMA CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; LIVER CELL CULTURE; LIVER DEVELOPMENT; MALE; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; SURVIVAL TIME; TOXICITY TESTING; URINALYSIS;

EID: 0034882338 PISSN: 1061186X EISSN: None Source Type: Journal
DOI: 10.3109/10611860108997927 Document Type: Article

Times cited : (18)

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