Radio-responsive recA promoter significantly increases TNFα production in recombinant clostridia after 2 Gy irradiation

Gene Therapy

Volumn 8, Issue 15, 2001, Pages 1197-1201

  Nuyts, S ^a,b   Van Mellaert, L ^a   Theys, J ^a   Landuyt, W ^b   Bosmans, E ^c   Anne J ^a   Lambin, P ^d  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^c DiaMed EuroGen   (Belgium)

^d MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Clostridium; Radio inducible promoter; Radiotherapy; recA; TNF

Indexed keywords

CYTOTOXIC AGENT; RECA PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANAEROBIC BACTERIUM; ANOXIA; ARTICLE; CANCER THERAPY; CLOSTRIDIUM; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DNA MODIFICATION; FEASIBILITY STUDY; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION; GENE INDUCTION; GENE TARGETING; GENE THERAPY; GENE TRANSFER; GENETIC CODE; IONIZING RADIATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RADIATION DOSE; RADIATION DOSE FRACTIONATION; RADIOTHERAPY; RECOMBINANT DNA TECHNOLOGY;

CLOSTRIDIUM; DOSE FRACTIONATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GENE THERAPY; GENETIC VECTORS; HUMANS; NEOPLASMS; REC A RECOMBINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034881875     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301499     Document Type: Article

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