Sequence-dependent cytotoxicity of combination chemotherapy using paclitaxel, carboplatin and bleomycin in human lung and ovarian cancer

Anti-Cancer Drugs

Volumn 12, Issue 7, 2001, Pages 595-602

  Waltmire, Caroline N ^a   Alberts, David S ^a   Dorr, Robert T ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

Bleomycin; Carboplatin; Combination chemotherapy; Isobologram; Paclitaxel

Indexed keywords

BLEOMYCIN; BLEOMYCIN SULFATE; CARBOPLATIN; PACLITAXEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CANCER CELL; CELL CYCLE G2 PHASE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BLEOMYCIN; BODY WEIGHT; CARBOPLATIN; CARCINOMA, NON-SMALL-CELL LUNG; CYSTADENOCARCINOMA; DRUG SYNERGISM; FEMALE; FLOW CYTOMETRY; HUMANS; LUNG NEOPLASMS; MALE; MICE; MICE, SCID; OVARIAN NEOPLASMS; PACLITAXEL; TUMOR CELLS, CULTURED;

EID: 0034881202     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-200108000-00006     Document Type: Article

References (30)

1. Paclitaxel (Taxol): A novel anticancer chemotherapeutic drug
2. Paclitaxel
3. Carboplatin
4. Treatment strategies for metastatic non-small-cell lung cancer
5. Improved therapeutic index of carboplatin plus cyclophosphamide versus cisplatin plus cyclophosphamide: Final report by the Southwest Oncology Group of a phase III randomized trial in stages III and IV ovarian cancer
6. Chemistry and mechanism of action of bleomycin
7. Bleomycin sulfate
8. Chemotherapy of ovarian cancer directed by the human tumor stem cell assay
9. Bleomycin
10. Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
11. Comparative properties of five human ovarian adenocarcinoma cell lines
12. New colorimetric cytotoxicity assay for anticancer-drug screening
13. Terminology in the description of drug-radiation interactions
14. A link between double-strand break-related repair and V(D)J recombination: The scid mutation
15. Human tumor models in the severe combined immune deficient (scid) mouse
16. Multiple comparisons
17. Experimental antitumor activity of taxotere (RP 56976, NSC 628503), a taxol analogue
18. Pharmacokinetics of paclitaxel administered in combination with cisplatin, etoposide and bleomycin in patients with advanced solid tumours
19. Management of intermediate-prognosis germ-cell cancer: Results of a phase I/II study of Taxol-BEP
20. Paclitaxel steady-state plasma concentration as a determinant of disease outcome and toxicity in lung cancer patients treated with paclitaxel and cisplatin
21. Phase I trial, including pharmacokinetic and pharmacodynamic correlations, of combination paclitaxel and carboplatin in patients with metastatic non-small-cell lung cancer
22. Clinical pharmacology of carboplatin administered in combination with paclitaxel
23. A comparative study of the cytotoxicity and DNA-damaging effects of cis-(diammino)(1,1-cyclobutanedicarboxylato)-platinum(II) and cis-diamminedichloroplatinum(II) on L1210 cells
24. 1-S arresting agents observed in experimental combination therapy
25. Schedule-dependent interactions between paclitaxel and etoposide in human carcinoma cell lines in vitro
26. Sequence-dependent cytotoxicity of etoposide and paclitaxel in human breast and lung cancer cell lines
27. In vitro schedule-dependent interaction between paclitaxel and SN-38 (the active metabolite of irinotecan) in human carcinoma cell lines
28. Sequence-dependent alteration of doxorubicin pharmacokinetics by paclitaxel in a phase I study of paclitaxel and doxorubicin in patients with metastatic breast cancer
29. Phase I and pharmacologic study of sequences of paclitaxel and cyclophosphamide supported by granulocyte colony-stimulating factor in women with previously treated metastatic breast cancer
30. The effect of anticancer drug sequence in experimental combination chemotherapy