First clinical isolate of Streptococcus pneumoniae exhibiting high-level resistance to fluoroquinolones in Taiwan [2]

Journal of Antimicrobial Chemotherapy

Volumn 48, Issue 2, 2001, Pages 316-317

  Hsueh, Po Ren ^a,b   Teng, Lee Jene ^a,c   Wu, Tsu Lan ^d   Ho, Shen Wu ^a,c   Luh, Kwen Tay ^a,b  

^a Departments of Medicine   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; CHLORAMPHENICOL; CIPROFLOXACIN; CLARITHROMYCIN; CLINDAMYCIN; COTRIMOXAZOLE; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE IV; MOXIFLOXACIN; OFLOXACIN; PENICILLIN G; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RESERPINE; TETRACYCLINE; TROVAFLOXACIN; VANCOMYCIN;

AGED; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; BACTERIUM ISOLATE; DILUTION; HUMAN; LETTER; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; POINT MUTATION; STREPTOCOCCUS PNEUMONIAE; TAIWAN;

ANTI-INFECTIVE AGENTS; DRUG RESISTANCE, BACTERIAL; FLUOROQUINOLONES; HUMANS; STREPTOCOCCUS PNEUMONIAE; TAIWAN;

EID: 0034879286     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Letter

References (6)

1. Involvement of topoisomerase IV and DNA gyrase as ciprofloxacin targets in Streptococcus pneumoniae
2. High-level fluoroquinolone resistance in Streptococcus pneumoniae requires mutations in parC and gyrA
3. Prevalence of gyrA, gyrB, parC, and parE mutations in clinical isolates of Streptococcus pneumoniae with decreased susceptibilities to different fluoroquinolones and originating from worldwide surveillance studies respiratory season
4. Apparent involvement of a multidrug resistant transporter in the fluoroquinolone resistance of Streptococcus pneumoniae
5. Prevalence of a putative efflux mechanism among fluoroquinolone-resistant clinical isolates of Streptococcus pneumoniae
6. Efflux and target mutations as quinolone resistance mechanisms in clinical isolates of Streptococcus pneumoniae