Fracture property studies of paracetamol single crystals using microindentation techniques

Pharmaceutical Research

Volumn 18, Issue 6, 2001, Pages 867-872

  Prasad, Korlakunte V R ^a,b   Sheen, David B ^a   Sherwood, John N ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Fracture toughness; Microindentation; Paracetamol; Single crystal

Indexed keywords

PARACETAMOL; PLASTIC;

ANALYTIC METHOD; ARTICLE; CHEMICAL ANALYSIS; CRYSTAL STRUCTURE; CRYSTALLIZATION; DRUG STRUCTURE; HARDNESS; PRIORITY JOURNAL; TABLET COMPRESSION;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; CRYSTALLIZATION; HARDNESS TESTS; SURFACE PROPERTIES;

EID: 0034872091     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011005016677     Document Type: Article

References (21)

1. Mechanical Properties
2. Indentation fracture: Principles and applications
3. Microfracture beneath point indentations in brittle solids
4. A critical evaluation of indentation techniques for measuring toughness: I, direct crack measurements
5. Direct observation and analysis of indentation cracking in glasses and ceramics
6. Evaluating the hardness, Young's modulus and fracture toughness of some pharmaceutical crystals using microindentation techniques
7. Evaluating the deformation kinetics of sucrose crystals using Microindentation techniques
8. Vickers hardness testing of sucrose single crystals
9. Materials for direct compaction
10. Indentation hardness testing of tablets
11. Microhardness and dislocation identification studies on paracetamol single crystals
12. Characterisation of growth behavior of small paracetamol crystals grown from pure solutions
13. Hardness anisotropy of acetaminophen crystals
14. New formula for indentation toughness in ceramics
15. The work for the formation of a crack during Vickers indentaion as a measure of the toughness of hard metals
16. Elastic/plastic indentation damage in ceramics: The lateral crack system
17. HABIT - A programme for predicting the morphology of molecular crystals
18. HABIT 95 - A program for predicting the morphology of molecular crystals as a function of the growth environment
19. A theoretical examination of the molecular packing, intermolecular bonding and crystal morphology of 2,4,6-trinitrotoluene in relation to polymorphic structural stability
20. Energy parameters in polypeptides. VII Geometric parameters, partial atomic charges, non-bonded interactions and intrinsic torsional potentials for the naturally occuring amino acids