Monitoring clinical trials with multiple arms

Biometrics

Volumn 57, Issue 3, 2001, Pages 892-898

  Hellmich, M ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Adaptive interim analysis; Closed testing; Group sequential trials; Multiple testing; Multiple treatments

Indexed keywords

ERROR ANALYSIS;

ADAPTIVE INTERIM ANALYSE; CLINICAL TRIAL; CLOSED TESTING; GROUP SEQUENTIAL TRIAL; INTERIM ANALYSIS; LARGE GROUPS; MULTIPLE ARMS; MULTIPLE TESTING; MULTIPLE TREATMENT; SEQUENTIAL CLINICAL TRIALS;

MEDICAL APPLICATIONS;

BIOMETRY;

ADAPTATION; ANALYSIS; ARTICLE; ECONOMIC ASPECT; ETHICS; METHODOLOGY; MONITORING; STATISTICS;

EID: 0034870726     PISSN: 0006341X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0006-341X.2001.00892.x     Document Type: Article

References (25)

1. Combining different phases in the development of medical treatments within a single trial
2. Evaluation of experiments with adaptive interim analyses
3. An adaptive method for establishing a dose-response relationship
4. Rationale and design for the Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
5. Monitoring pairwise comparisons in multi-armed clinical trials
6. A simple sequentially rejective multiple test procedure
7. Interim analysis: The repeated confidence interval approach
8. 2 and F tests
9. Inference on multiple endpoints in clinical trials with adaptive interim analysis
10. Discrete sequential boundaries for clinical trials
11. Adaptive sample size calculations in group sequential trials
12. A group sequential procedure for all-pairwise comparisons of k treatments based on the range statistic
13. On closed testing procedures with special reference to ordered analysis of variance
14. A multiple testing procedure for clinical trials
15. Group sequential methods in the design and analysis of clinical trials
16. Adaptive two stage designs and the conditional error function
17. Designed extensions of studies based on conditional power
18. Monitoring multi-armed trials
19. R: A language for data analysis and graphics
20. Closed testing procedures for group sequential clinical trials with multiple endpoints
21. Multistage adaptive test procedures based on Fisher's product criterion
22. Effects of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women. The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial