Gene cluster on pAO1 of Arthrobacter nicotinovorans involved in degradation of the plant alkaloid nicotine: Cloning, purification, and characterization of 2,6-dihydroxypyridine 3-hydroxylase

Journal of Bacteriology

Volumn 183, Issue 18, 2001, Pages 5262-5267

  Baitsch, D ^a   Sandu, C ^a   Brandsch, R ^a   Igloi, G L ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2,6 DIHYDROXYPYRIDINE 3 HYDROXYLASE; ALKALOID; FLAVINE ADENINE NUCLEOTIDE; MOLYBDOPTERIN; NICOTINE; OXYGENASE; UNCLASSIFIED DRUG;

ARTHROBACTER; ARTHROBACTER NICOTINOVORANS; ARTICLE; DEGRADATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PURIFICATION; ENZYME SUBUNIT; GENE CLUSTER; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ARTHROBACTER; BIODEGRADATION, ENVIRONMENTAL; CLONING, MOLECULAR; GENES, BACTERIAL; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; NICOTINE; OPEN READING FRAMES; PLASMIDS; PYRIDINES;

ACTINOBACTERIA (CLASS); ARTHROBACTER; ARTHROBACTER NICOTINOVORANS; ESCHERICHIA COLI; PROKARYOTA; UNCULTURED ACTINOMYCETE;

EID: 0034868291     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.183.18.5262-5267.2001     Document Type: Article

References (35)

1. Basic local alignment search tool
2. Purification of recombinant antigenic epitopes on the human 68-kDa (U1) ribonucleoprotein antigen using the expression system pH6EX3 followed by metal chelating affinity chromatography
3. A new DNA sequence assembly program
4. A new family of carbon-nitrogen hydrolases
5. Isolation and partial characterization of plasmid DNA from Arthrobacter oxydans
6. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
7. Purification and properties of L-6-hydroxynicotine oxidase
8. Über den abbau des nikotins durch bakterienenzyme. III. Stoffwechselstudien an zellfreien extrakten
9. Induction and purification of stereospecific nicotine oxidizing enzymes from Arthrobacter oxydans
10. Über den abbau des nikotins durch bakterienenzyme. II. Isolierung und charakterisierung eines nikotinabbauenden bodenbakteriums
11. Identification of a novel conserved sequence motif in flavoprotein hydroxylases with a putative dual function in FAD/NAD(P)H binding
12. Purification and properties of 4-hydroxybenzoate 1-hydroxylase (decarboxylating), a novel flavin adenine dinucleotide-dependent monooxygenase from Candida parapsilosis CBS604
13. Phe161 and Arg166 variants of p-hydroxybenzoate hydroxylase implications for NADPH recognition and structural stability
14. The metabolism of nicotinic acid. I. Purification and properties of 2,5-dihydroxypyridine oxygenase from Pseudomonas putida N-9
15. The bacterial oxidation of nicotine. VI. The metabolism of 2,6-dihydroxypseudooxynicotine
16. Structural analysis and molybdenum-dependent expression of the pAO1-encoded nicotine dehydrogenase genes of Arthrobacter nicotinovorans
17. Regulation of flavoprotein synthesis in vivo in a riboflavin-requiring mutant of Arthrobacter oxidans
18. Effect of molybdate and tungstate on the biosynthesis of CO dehydrogenase and the molybdopterin cytosine-dinucleotide-type of molybdenum cofactor in Hydrogenophaga pseudoflava
19. The bacterial oxidation of nicotine. VII. Partial purification and properties of 2,6-dihydoxypyridine oxidase
20. The bacterial oxidation of nicotine. VIII. Synthesis of 2,3,6-trihydroxypyridine and accumulation and partial characterization of the product of 2,6-dihydoxypyridine oxidation
21. Reversible resolution and reconstitution of flavoproteins into apoproteins and free flavin
22. Reclassification of two strains of Arthrobacter oxydans and proposal of Arthrobacter nicotinovorans sp. nov.
23. The Streptomyces peucetius dpsY and dnrX genes govern early and late steps of daunorubomycin and doxorubicin biosynthesis
24. Cloning, nucleotide sequence, and heterologous expression of the biosynthetic gene cluster for R1128, a non-steroidal estrogen receptor antagonist. Insights into an unusual priming mechanism
25. Functional dissection of the molybdate-responsive transcription regulator, ModE, from Escherichia coli
26. IS1473, a putative insertion sequence identified in the plasmid pAO1 from Arthrobacter nicotino-vorans: Isolation, characterization and distribution among Arthrobacter species
27. Molybdate-uptake genes and molybdopterin-biosynthesis genes on a bacterial plasmid
28. Sequence analysis, characterization and CO-specific transcription of the cox gene cluster on the megaplasmid pHCG3 of Oligotropha carboxidovorans
29. Gene structure and properties of enzymes of the plasmid-encoded nicotine catabolism of Arthrobacter nicotinovorans
30. Horizontal gene transfer involved in the convergent evolution of the plasmid-encoded enantioselective 6-hydroxynicotine oxidases
31. Transcriptional regulation of molybdoenzyme synthesis in Escherichia coli in response to molybdenum: ModE-molybdate, a repressor of the modABCD (molybdate transport) operon is a secondary, transcriptional activator for the hyc and nar operons
32. 4-Hydroxybenzoate hydroxylase from Pseudomonas sp. CBS3. Purification, characterization, gene cloning, sequence analysis and assignment of structural features determining the coenzyme specificity
33. Overexpression of salicylate hydroxylase and the crucial role of lys(163) as its NADH binding site
34. Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis