Midazolam disposition in patients undergoing continuous venovenous hemodialysis

Journal of Clinical Pharmacology

Volumn 41, Issue 9, 2001, Pages 959-962

  Bolon, M ^a   Bastien, O ^a   Flamens, C ^a   Paulus, S ^a   Boulieu, R ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; MIDAZOLAM;

ACUTE KIDNEY FAILURE; ADULT; AGED; ARTICLE; CASE REPORT; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG CONJUGATION; DRUG DISPOSITION; DRUG ELIMINATION; DRUG GLUCURONIDATION; DRUG HALF LIFE; DRUG INFUSION; HEMODIALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTENSIVE CARE UNIT; ULTRAFILTRATION;

AGED; ANURIA; AREA UNDER CURVE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; GLUCURONIDES; HALF-LIFE; HEMOFILTRATION; HUMANS; HYPNOTICS AND SEDATIVES; INTENSIVE CARE; KIDNEY FUNCTION TESTS; MALE; MIDAZOLAM; MIDDLE AGED; ULTRAFILTRATION;

EID: 0034867407     PISSN: 00912700     EISSN: None     Source Type: Journal    
DOI: 10.1177/00912700122010933     Document Type: Article

References (7)

1. Midazolam, a review of its pharmacological properties and therapeutic use
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3. Prolonged sedation due to accumulation of conjugated metabolites of midazolam
4. Determination of midazolam and its unconjugated 1-hydroxy metabolite in human plasma by high-performance liquid chromatography
5. The effects of acute changes in renal function on the pharmacokinetics of midazolam during long-term infusion in ICU patients
6. Drug removal during continuous hemofiltration or hemodialysis
7. Protein binding of oxazepam and its glucuronide conjugates to human albumin