Heavy metal detoxification in plants: Phytochelatin biosynthesis and function

IUBMB Life

Volumn 51, Issue 3, 2001, Pages 183-188

  Cobbett, C S ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Arabidopsis; Glutathione; Heavy metal detoxification; Phytochelatins

Indexed keywords

CADMIUM; GLUTATHIONE; HEAVY METAL; PHYTOCHELATIN; PHYTOCHELATIN SYNTHASE;

AMINO ACID SEQUENCE; ARABIDOPSIS; BIOSYNTHESIS; DETOXIFICATION; ENZYME ACTIVATION; ENZYME SUBSTRATE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLANT; PROTEIN SYNTHESIS; REVIEW; SCHIZOSACCHAROMYCES POMBE;

ANIMALIA; ARABIDOPSIS; ARABIDOPSIS THALIANA; SCHIZOSACCHAROMYCES POMBE;

EID: 0034864183     PISSN: 15216543     EISSN: None     Source Type: Journal    
DOI: 10.1080/152165401753544250     Document Type: Review

References (25)

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2. Structure and function of metal chelators produced by plants. The case for organic acids, amino acids, phytin and metallothioneins
3. Phytochelatins, a class of heavy-metal-binding peptides from plants are functionally analogous to metallothioneins
4. Structure of cadystin, the unit peptide of cadmium-binding peptides induced in the fission yeast Schizosaccharomyces pombe
5. Phytochelatins and their roles in heavy metal detoxification
6. Phytochelatins, the heavy-metal-binding peptides of plants, are synthesized from glutathione by a specific γ-glutamylcysteine dipeptidyl transpeptidase (phytochelatin synthase)
7. Cadmium-sensitive mutants of Arabidopsis thaliana
8. A new vertical mesh transfer technique for metaltolerance studies in Arabidopsis-ecotypic variation and copper-sensitive mutants
9. A cadmium-sensitive, glutathione-deficient mutant of Arabidopsis thaliana
10. Arabidopsis thaliana γ-glutamylcysteine synthetase is structurally unrelated to mammalian, yeast and Escherichia coli homologs
11. The glutathione-deficient, cadmium-sensitive mutant, cad2-1 of Arabidopsis thaliana is deficient in γ-glutamylcysteine synthetase
12. The Root Meristemlessi/Cadmium Sensitive2 gene defines a glutathione-dependent pathway involved in initiation and maintenance of cell division during postembyronic root development
13. Cadmium-sensitive, cad1, mutants of Arabidopsis thaliana are phytochelatin deficient
14. Phytochelatin synthase genes from Arabidopsis and the yeast, Schizosaccharomyces pombe
15. AtPCS1, a phytochelatin synthase from Arabidopsis: Isolation and in vitro reconstitution
16. Tolerance to toxic metals by a gene family of phytochelatin synthases from plants and yeast
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18. Glutathione homeostasis in plants: Implications for environmental sensing and plant development
19. Characterization of phytochelatin synthase from tomato
20. Mechanism of heavy metal ion activation of phytochelatin(PC) synthase: Blocked thiols are sufficient for PC synthase-catalyzed transpeptidation of glutathione and related thiol peptides
21. A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCFI-catalyzed transport of bis(glutathionato) cadmium
22. Transport of metal-binding peptides by HMT1, a fission yeast ABC-type vacuolar membrane protein
23. Purine biosynthetic genes are required for cadmium tolerance in Schizosaccharomyces pombe
24. A role for HEM2 in cadmium tolerance