An exact test for the association between the disease and alleles at highly polymorphic loci with particular interest in the haplotype analysis

Biometrics

Volumn 57, Issue 3, 2001, Pages 769-778

  Hirotsu, Chihiro ^a   Aoki, Satoshi ^b   Inada, Toshiya ^c   Kitao, Yoshie ^c  

^a MEISEI UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (Japan)

Author keywords

Allele frequencies; Amalgamation noninvariance; Haplotype analysis; Markov property; Max accumulated X2; Max one to others X2; Two and three way associations

Indexed keywords

ASSOCIATION REACTIONS; DNA SEQUENCES; GENES; PROBABILITY DISTRIBUTIONS;

ALLELE FREQUENCY; AMALGAMATION NONINVARIANCE; EXACT TESTS; HAPLOTYPE ANALYSE; HAPLOTYPES; MARKOV PROPERTY; MAX ACCUMULATED X2; MAX ONE-TO-OTHER X2; TWO WAYS; TWO-WAY AND THREE-WAY ASSOCIATION;

STATISTICAL TESTS;

DISEASE; GENETICS; STATISTICAL ANALYSIS;

ALLELE; ARTICLE; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC DISORDER; GENETIC POLYMORPHISM; HAPLOTYPE; QUANTITATIVE GENETICS;

EID: 0034862767     PISSN: 0006341X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0006-341X.2001.00769.x     Document Type: Article

References (8)

1. Survey of the fragile X syndrome CGG repeat and the short-tandem-repeat and single-nucleotide-polymorphism haplotypes in an African American population
2. Multiplicative and additive interaction in contingency tables
3. Use of cumulative efficient scores for testing ordered alternatives in discrete models
4. Multiple comparison procedures based on the maximal component of the cumulative chi-squared statistic
5. Change point analysis as a method for isotonic interference
6. Linkage disequilibrium between the fragile X mutation and two closely linked CA repeats suggests that fragile X chromosomes are derived from a small number of founder chromosomes
7. Monte Carlo tests for associations between disease and alleles at highly polymorphic loci