Synthesis of unnatural 7-substituted-1-(2-deoxy-β-D-ribofuranosyl)isocarbostyrils: "Thymine replacement" analogs of deoxythymidine for evaluation as antiviral and anticancer agents

Nucleosides, Nucleotides and Nucleic Acids

Volumn 20, Issue 8, 2001, Pages 1533-1553

  Naimi, Ebrahim ^a   Duan, Weili ^a   Wiebe, Leonard I ^a   Knaus, Edward E ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2 DEOXY BETA DEXTRO RIBOFURANOSYL) 7 (2 BROMOETHYNYL)ISOCARBOSTYRIL; 1 (2 DEOXY BETA DEXTRO RIBOFURANOSYL) 7 (2 IODOVINYL)ISOCARBOSTYRIL; 1 (2 DEOXY BETA DEXTRO RIBOFURANOSYL) 7 CYANOISOCARBOSTYRIL; 1 (2 DEOXY BETA DEXTRO RIBOFURANOSYL) 7 ETHYNYLISOCARBOSTYRIL; 1 (2 DEOXY BETA DEXTRO RIBOFURANOSYL) 7 IODOETHYNYLCARBOSTYRIL; 1 (2 DEOXY BETA DEXTRO RIBOFURANOSYL) 7 IODOISOCARBOSTYRIL; 1 (2 DEOXY BETA DEXTRO RIBOFURANOSYL) 7 PROPYNYLISOCARBOSTYRIL; 1 (2 DEOXY BETA DEXTRO RIBOFURANOSYL) 7 TRIFLUOROMETHYLISOCARBOSTYRIL; 1 (2 DEOXY BETA DEXTRO RIBOFURANOSYL)ISOCARBOSTYRIL; 1 [3,5 BIS O (4 CHLOROBENZOYL) BETA DEXTRO RIBOFURANOSYL] 4,7 DINITROISOCARBOSTYRIL; ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; THYMIDINE; THYMIDINE DERIVATIVE; THYMIDINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CANCER CELL; CYTOTOXICITY; DRUG SYNTHESIS; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; MOUSE; NONHUMAN;

ANIMALS; ANTICARCINOGENIC AGENTS; ANTIVIRAL AGENTS; DNA REPLICATION; HUMANS; ISOQUINOLINES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; THYMIDINE; TUMOR CELLS, CULTURED;

ANIMALIA; HERPES; HUMAN HERPESVIRUS 1;

EID: 0034862168     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-100105246     Document Type: Article

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