Genetic analysis of the organic cation transporter genes Orct2/Slc22a2 and Orct3/Slc22a3 reduces the critical region for the t haplotype mutant tw73 to 200 kb

Mammalian Genome

Volumn 12, Issue 9, 2001, Pages 734-740

  Zwart, Ronald ^a   Verhaagh, Sandra ^a   De Jong, Jeroen ^a   Lyon, Mary ^b   Barlow, Denise P ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b MRC MAMMALIAN GENETICS UNIT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CATION TRANSPORT; CHROMOSOME 17; CONTROLLED STUDY; DNA POLYMORPHISM; GENETIC ANALYSIS; GENETIC COMPLEMENTATION; HAPLOTYPE; HOMOZYGOTE; MALE FERTILITY; MOUSE; NIDATION; NONHUMAN; NORTHERN BLOTTING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING; TRANSGENE;

ANIMALS; BLOTTING, NORTHERN; BLOTTING, SOUTHERN; CARRIER PROTEINS; CHROMOSOMES, ARTIFICIAL, YEAST; CROSSES, GENETIC; DNA PRIMERS; EMBRYONIC DEVELOPMENT; FEMALE; GENETIC COMPLEMENTATION TEST; HAPLOTYPES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, TRANSGENIC; MICROTUBULE-ASSOCIATED PROTEINS; MUTATION; NUCLEAR PROTEINS; ORGANIC CATION TRANSPORT PROTEINS; ORGANIC CATION TRANSPORTER 1; POLYMORPHISM, GENETIC; PREGNANCY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA;

ANIMALIA; RODENTIA;

EID: 0034861748     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00335-001-3016-8     Document Type: Article

References (47)

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29. Segregation distortion of mouse t haplotypes the molecular basis emerges
30. The mouse plasminogen locus maps to the recombination breakpoints of the tLub2 and TtOr1 partial t haplotypes but is not at the tw73 locus
31. The Lx1 gene maps to mouse chromosome 17 and codes for a protein that is homologous to glucose and polyspecific transmembrane transporters
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34. Mouse t haplotypes
35. Embryological study of a T/t locus mutation (tw73) affecting trophectoderm development
36. Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27
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43. Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain
44. Imprinted expression of the Igf2r gene depends on an intronic CpG island
45. Deletion of region 2 restores biallelic expression of the imprinted Igf2r gene and decreases fetal and adult growth in mice
46. Impaired activity of the Extraneuronal Monoamine Transporter System known as Uptake-2 in Orct31Slc22a3 deficient mice
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