Recovery from oxidant-mediated lung injury: Response of metallothionein, MIP-2, and MCP-1 to nitrogen dioxide, oxygen, and ozone exposures

Inhalation Toxicology

Volumn 13, Issue 8, 2001, Pages 689-702

  Johnston, C J ^a   Oberdorster G ^a   Finkelstein, J N ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MACROPHAGE INFLAMMATORY PROTEIN 2; METALLOTHIONEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; NITROGEN DIOXIDE; OXIDIZING AGENT; OXYGEN; OZONE; REACTIVE OXYGEN METABOLITE; SCAVENGER;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; EXPOSURE; INFLAMMATORY CELL; LUNG INJURY; LUNG LAVAGE; MACROPHAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PNEUMONIA; PRIORITY JOURNAL; RIBONUCLEASE PROTECTION ASSAY;

ANIMALIA;

EID: 0034857213     PISSN: 08958378     EISSN: None     Source Type: Journal    
DOI: 10.1080/08958370152409919     Document Type: Article

References (42)

1. Silica-induced chemokine expression in alveolar type II cells is mediated by TNF-α-induced oxidant stress
2. Antioxidant treatment attenuates cytokine and chemokine levels in murine macrophages following silica exposure
3. A reversible model of acute lung injury based on ozone exposures
4. Lung injury, inflammation and inflammatory stimuli in rats exposed to ozone
5. Effect of acute inflammatory lung injury on the expression of monocyte chemoattractant protein-1 (MCP-1) in rat pulmonary alveolar macrophages
6. Effect of oxidant pollutants on the respiratory system: Insights from experimental animal research
7. Morphologic changes in pulmonary oxygen toxicity
8. Structural and biochemical changes in rat lungs occurring during exposures to lethal and adaptive doses of oxygen
9. Chemokine mRNA alterations in newborn and adult mouse lung during acute hyperoxia
10. Ozone inhalation stimulates expression of a neutrophil chemotactic protein, macrophage inflammatory protein 2
11. α-Quartz-induced chemokine expression by rat lung epithelial cell: Effects of in vivo and in vitro particle exposure
12. Oxidant gases
13. 3
14. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
15. Oxygen therapy: Side effects and toxicity
16. Oxygen toxicity in neonatal and adult animals of various species
17. Hyperoxia increases oxygen radical production in rat lungs and mitochondria
18. Dexamethasone inhibits ozone-induced gene expression of macrophage inflammatory protein-2 in rat lung
19. Inter-strain variations in susceptibility to hyperoxic injury of murine airways
20. The effects of ozone on the respiratory epithelium of mice. II. Ultrastructural alterations
21. Biochemical effects of combined gases of nitrogen dioxide and ozone. III. Synergistic effects on lipid peroxidation and antioxidant protective systems in the lungs of rats and guinea pigs
22. Pulmonary inflammatory responses and cytokine and antioxidant mRNA levels in the lungs of young and old C57BL/6 mice after exposure to Teflon fumes
23. Inflammatory and antioxidant gene expression in C57BL/6J mice after lethal and sublethal ozone exposures
24. Clara cell secretory protein-deficient mice differ from wild-type mice in inflammatory chemokine expression to oxygen and ozone but not to endotoxin
25. Antioxidant and inflammatory response after acute nitrogen dioxide and ozone exposures in C57BI/6 mice
26. A genetic model for evaluation of susceptibility to ozone-induced inflammation
27. Susceptibility to ozone induced inflammation. I. Genetic control of the response to subacute exposure
28. Differential susceptibility to oxidant exposure in inbred strains of mice: Nitrogen dioxide versus ozone
29. Clara cell secretory protein deficiency increases oxidant stress response in conducting airways
30. Biochemical basis of ozone toxicity
31. Biochemical and metabolic changes in the lung with oxygen, ozone, and nitrogen dioxide toxicity
32. Increased expression of tissue inhibitor of metalloproteinases (TIMP-1) and metallothionein in murine lungs after hyperoxic exposure
33. Overexpression of metallothionein decreases sensitivity of pulmonary endothelial cells to oxidant injury
34. 2 reactive absorption substrates in rat pulmonary surface lining fluids
35. A new mechanism for the toxicity of ozone
36. Regulation of antioxidant enzymes in the lung after oxidant injury
37. JE/MCP-1: An early response gene encodes a monocyte-specific cytokine
38. Oxygen free radicals and metallothionein
39. Hybridization of denatured RNA transferred or dotted to nitrocellulose paper
40. Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanisms of its reaction with superoxide and hydroxyl radicals
41. Cytokine expression by neutrophils and macrophages in vivo: Endotoxin induces tumor necrosis factor-α, macrophage inflammatory protein-2, interleukin-1β, and interleukin-6 but not RANTES or transforming growth factor-β1, mRNA expression in acute lung inflammation
42. Chemokine regulation of ozone-induce neutrophil and monocyte inflammation