Growth hormone: Its measurement and the need for assay harmonization

Annals of Clinical Biochemistry

Volumn 38, Issue 5, 2001, Pages 471-482

  Wood, P ^a  

^a SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; HUMAN GROWTH HORMONE; PLACENTA LACTOGEN; POLYCLONAL ANTIBODY;

ACROMEGALY; ALTERNATIVE RNA SPLICING; ASSAY; CALIBRATION; ENZYME SPECIFICITY; GENETIC HETEROGENEITY; GROWTH HORMONE RELEASE; HORMONE DETERMINATION; HUMAN; MEASUREMENT; PRIORITY JOURNAL; PROVOCATION TEST; QUALITY CONTROL; REVIEW;

BIAS (EPIDEMIOLOGY); BIOLOGICAL ASSAY; CALIBRATION; GROWTH HORMONE; HUMANS; IMMUNOASSAY; MOLECULAR WEIGHT; PROTEIN BINDING; PROTEIN ISOFORMS; SENSITIVITY AND SPECIFICITY;

EID: 0034856622     PISSN: 00045632     EISSN: None     Source Type: Journal    
DOI: 10.1258/0004563011901280     Document Type: Review

References (41)

1. Physiology of growth hormone secretion and action
2. Human growth hormone: Additional members of the complex
3. Human growth hormone peptide 1-43: Isolation from pituitary glands
4. Human growth hormone (hGH)-(44-191), a reportedly diabetogenic fragment of hGH, circulates in human blood: Measurement by radioimmunoassay
5. Growth hormone heterogeneity in human pituitary and plasma
6. Plasma 'big' and 'big-big' growth hormone (GH) in man: An oligomeric series composed of structurally diverse GH monomers
7. Human growth hormone: Perspective on its chemistry and biology
8. Isolation of dimeric forms of pituitary growth hormone by bioassay, radioreceptor assay and radioimmunoassay
9. An interchain disulphide dimer of human growth hormone
10. Growth hormone heterogeneity: Genes, isohormones, variants and binding proteins
11. The half life of exogenous growth hormone after suppression of endogenous growth hormone secretion with somatostatin
12. The physiology of growth hormones (GHs) in pregnant women and partial characterisation of the placental GH variant
13. Regulation of plasma growth hormone-binding proteins in health and disease
14. Laron dwarfism: Typical and atypical forms
15. Identification of transformed alpha 2-macroglobulin as a growth hormone binding protein in human blood
16. ESTA: A bioassay system for the determination of the potencies of hormones and antibodies which mimic their action
17. The measurement of growth hormone bioactivity in patients' serum using an eluted stain assay
18. Evaluation of growth hormone (GH) responses to pulsed GH-releasing hormone administration using the MTT-ESTA bioassay
19. 22 kD Growth hormone exclusion assay: A new approach to measurement of non-22 kD growth hormone isoforms in human blood
20. Increased proportion of circulating non-22-kilodalton isoforms in short children: A possible mechanism for growth failure
21. Circulating non-22-kilodalton growth hormone isoforms in acromegalic men before and after transsphenoidal surgery
22. Serum concentration of 20K human growth hormone (20K hGH) measured by a specific enzyme-linked immunosorbent assay
23. Serum levels of 20-kilodalton human growth hormone (GH) are parallel those of 22-kilodalton human GH in normal and short children
24. Dimerisation of the extracellular domain of the human growth hormone receptor by a single hormone molecule
25. Growth hormone receptor signalling
26. Immunofunctional assay of human growth hormone (hGH) in serum: A possible consensus for qualitative hGH measurement
27. Growth hormone binding protein determination in plasma: A comparison of immunofunctional and growth hormone-binding assays
28. Immunofunctional and immunometric serum growth hormone assays compared for the assessment of stimulation test responses
29. Serum growth hormone measurements in clinical practice: An audit of performance from the UK National External Quality Assessment Scheme
30. Assay of growth hormone levels in human plasma using commercial kits: Analysis of some factors influencing the results
31. Cross-reactivity of monomeric and dimeric biosynthetic human growth hormone in a commercial immunoassay
32. Certain large forms of circulating immunoreactive human growth hormone are in fact immunoglobulins
33. Influence of matrix on concentrations of somatotropin measured in serum with commercial immunoradiometric assays
34. Effects of growth hormone-binding proteins on serum growth hormone measurements
35. Influence of growth hormone binding protein on growth hormone estimation in different immunoassays
36. Variety in growth hormone determinations due to use of different immunoassays and the interference of growth hormone binding protein
37. Experience with human growth hormone in Great Britain: The report of the MRC Working Party
38. What is a normal stimulated growth hormone concentration?
39. Diagnosis of human growth hormone deficiency: An assay dependent phenomenon?
40. Interpretation of growth hormone provocative tests: Comparison of cut-off values in four European laboratories
41. Consensus on how to measure growth hormone in serum