Nonspecific human IgG reduces survival in neonatal rats infected with Escherichia coli

American Journal of the Medical Sciences

Volumn 322, Issue 3, 2001, Pages 141-144

  Cole, Cameron W ^a   Feldhoff, Richard C ^a   Goldsmith, L Jane ^a   Jung, Erzsebet ^a   Wilson, Richard A ^b   Lassiter, Herbert A ^a  

^a University of Louisville School of Medicine   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

IgG; Intravenous immunoglobulin; Neonatal sepsis

Indexed keywords

IMMUNOGLOBULIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; PENICILLIN DERIVATIVE;

ANIMAL MODEL; ANTIBODY TITER; ARTICLE; BACTERIAL INFECTION; COMPLEMENT ACTIVATION; CONTROLLED STUDY; ESCHERICHIA COLI; GRAM NEGATIVE INFECTION; HEMOLYSIS; NEWBORN; NEWBORN SEPSIS; NONHUMAN; RAT; SURVIVAL RATE;

EID: 0034856283     PISSN: 00029629     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000441-200109000-00006     Document Type: Article

References (16)

1. Modified human immune serum globulin for intravenous administration: In vitro opsonic activity and in vivo protection against group B streptococcal disease in suckling rats
2. Opsonic antibodies to Staphylococcus epidermidis: In vitro and in vivo studies using human intravenous immune globulin
3. Human immunoglobulins for intravenous use. Comparison of available preparations for group B streptococcal antibody levels, opsonic activity, and efficacy in animal models
4. Meta-analysis of the effectiveness of intravenous immune globulin for prevention and treatment of neonatal sepsis
5. Mechanisms of action of intravenous immune globulin in immune-mediated diseases
6. Mechanisms of intravenous immune globulin therapy in antibody-mediated autoimmune diseases
7. The administration of complement component C9 enhances the survival of neonatal rats with Escherichia coli sepsis
8. High intravenous doses of human immune globulin suppress neonatal group B streptococcal immunity in rats
9. High-dose intravenous immune globulin impairs antibacterial activity of antibiotics
10. Deleterious effect of immune globulin in the treatment of H. influenza B infection in infant rats
11. The effects of intravenous immune globulin on complement-dependent immune damage of cells and tissues
12. Mechanism of therapeutic effect of high-dose intravenous immunoglobulin. Attenuation of acute, complement-dependent immune damage in a guinea pig model
13. High doses of intravenous Ig inhibit in vitro uptake of C4 fragments onto sensitized erythrocytes
14. Bacteria and complement
15. High-dose intravenous immunoglobulin modifies complement-mediated in vivo clearance
16. Safety of a Staphylococcus aureus (SA) intravenous immunoglobulin (AltaStaph) in very-low- birthweight (VLBW) neonates