Characteristics of binding sites for ATP4- at the human P2X7 receptor

Drug Development Research

Volumn 53, Issue 2-3, 2001, Pages 77-82

  Klapperstück, Manuela ^a   Schmalzing, Günther ^b   Markwardt, Fritz ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Activation; Kinetics; P2X receptor; Whole cell current; Xenopus oocytes

Indexed keywords

ADENOSINE TRIPHOSPHATE; PURINE P2X RECEPTOR;

BINDING AFFINITY; BINDING SITE; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG EFFECT; HUMAN; HUMAN CELL; OOCYTE; PROTEIN EXPRESSION; RECEPTOR BINDING; VOLTAGE CLAMP; XENOPUS;

EID: 0034856248     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.1174     Document Type: Article

References (7)

1. Bretschneider F, Markwardt F. 1999. Dnig-dependent ion channel gating by application of concentration jumps using U-tube technique. Methods Enzymol 294:180-159.
2. Bretschneider F, Klapperstück M, Löhn M, Markwardt E 1995. Non-selective cationic currents elicited by extracellular ATP in human B-lymphocytes. Pflugers Arch 429:691-698.
3. Cameron DJ. 1984. Inhibition of macrophage mediated cytotoxicity by exogenous adenosine 5′-triphosphate. J Clin Lab Immunol 15:215-218.
4. 7 receptor. Br J Pharmacol 124:1314-1320.
5. Filippini A, Taffs RE, Agui T, Sitkovsky MV. 1990. Ecto-ATPase activity in cytolytic T-lymphocytes. J Biol Chem 265:334-340.
6. Horn R. 1987. Statistical methods for model discrimination: application to gating kinetics and permeation of the acetylcholine receptor channel. Biophys J 51:255-263.
7. Schubert R. 1990. A program for calculating multiple metal-ligand solutions. Comput Meth Progr Biomed 33:93-94.