The role of neurosteroids and nongenomic effects of progestins in the ventral tegmental area in mediating sexual receptivity of rodents

Hormones and Behavior

Volumn 40, Issue 2, 2001, Pages 226-233

  Frye, Cheryl A ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Allopregnanollone; GABA receptors; Hamsters; Lordosis; Mitochondrial benzodiazepine receptors; Neurosteroid; Nongenomic; Progesterone; Progestin; Rats; Sociosexual behavior

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR; BENZODIAZEPINE RECEPTOR; NEUROSTEROID; PROGESTERONE; PROGESTERONE RECEPTOR;

ANIMAL EXPERIMENT; CONFERENCE PAPER; CONTROLLED STUDY; DIESTRUS; FEMALE; HORMONAL REGULATION; HORMONE RECEPTOR INTERACTION; HYPOTHALAMUS; LORDOSIS; MATING; MESENCEPHALON; NONHUMAN; PRIORITY JOURNAL; PROESTRUS; SEXUAL BEHAVIOR; STEROIDOGENESIS; VENTRAL TEGMENTUM;

EID: 0034855948     PISSN: 0018506X     EISSN: None     Source Type: Journal    
DOI: 10.1006/hbeh.2001.1674     Document Type: Conference Paper

References (43)

1. Hypothalamic ovarian steroid hormone-sensitive neurons involved in female sexual behavior
2. Facilitation of sexual receptivity by hypothalmic and midbrain implants of progesterone in female hamsters
3. The excitation and inhibition of sexual receptivity in female hamsters by progesterone: Time and dose relationships, neural localization and mechanism of action
4. Progesterone may have membrane-mediated effects in rodent midbrain for inhibition of feminine sexual behavior
5. Inhibition of 5α-reductase enzyme in the VMH and VTA attenuates progesterone-induced sexual behavior in rats and hamsters
6. Mating stimuli influence endogenous variations in the neurosteroids 3α,5α-THP and 3α-Diol
7. Muscimol facilitates sexual receptivity in hamsters when infused into the ventral tegmentum
8. P-3-BSA, but not P-11-BSA, implants in the VTA rapidly facilitate receptivity in hamsters after progesterone priming to the VMH
9. Progestins can have a membrane-mediated action in rat midbrain for facilitation of sexual receptivity
10. Progestins can have a membrane-mediated action in rat midbrain for facilitation of sexual recepetivity that is likely GABA mediated
11. 5α-reduced progesterone metabolites are essential in hamster VTA for sexual receptivity
12. 3α,5α-THP in the ventral tegmental areas of rats and hamsters is increased in exogenous hormonal states associated with estrous cyclicity and sexual receptivity
13. A, D1, and D5, but not progestin receptor, antagonist and anti-sense oligonucleotide infusions to the ventral tegmental area of cycling rats and hamsters attenuate lordosis
14. Progesterone has rapid and membrane effects in the facilitation of female mouse sexual behavior
15. A receptor activity
16. Inhibitors of the biosynthesis and metabolism to 3α,5α-THP attenuate lordosis when applied to the VTA of rats and hamsters
17. Evidence for a non-genomic action of progestins on sexual receptivity in hamster ventral tegmental area but not hypothalamus
18. Bicuculline infused in the hamster ventral tegmentum inhibits, while sodium valproate facilitates, sexual receptivity
19. Behavioral effects of 3α-Androstanediol II: Hypothalamic and preoptic area actions via a GABAergic mechanism
20. A/benzodiazepine receptor complexes in the midbrain, are influenced by hormonal and reproductive state
21. Intravenous progesterone elicits a more rapid induction of lordosis in rats than does SKF38393
22. Anti-sense oligonucleotides for progesterone receptors block receptivity in the hypothalamus and glutamic acid decarboxylase in the mid-brain, block progesterone-induced lordosis in rats and hamsters
23. Estrous cycle and sex differences in performance on anxiety tasks coincide with increases in hippocampal progesterone and 3α,5α-THP
24. Structure-activity relationships for steroid interaction with the γ-aminobutyric acid A receptor complex
25. A receptors in rat cerebrocortical synaptoneurosomes
26. Membrane mechanism mediates progesterone stimulatory effect on LHRH release from superfused rat hypothalami in vitro
27. Binding of progesterone to nerve cell membranes of rat brain using progesterone conjugated to 125I-bovine serum albumin as a ligand
28. Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor
29. γ-aminobutyric acid mediates ventromedial hypothalamic mechanisms controlling the execution of lordotic responses in the female rat
30. Asymmetry in progestin receptor levels and sexual behavior in female rats
31. 3H]R5020
32. Action of estrogens and progestins on nerve cells
33. A contributory role for midbrain progesterone in the facilitation of female sexual behavior in rats
34. Application of anisomycin to the lateral ventromedial nucleus of the hypothalamus inhibits the activation of sexual behavior by estradiol and progesterone
35. Progesterone metabolism in the ventral tegmental area is important for lateral displacement and lordosis of hamsters
36. Brainstem influences on sexual behavior
37. Induction of estrous behavior in ovariectomized rats by sequential replacement of estrogen and progesterone to the ventromedial hypothalamus
38. Diencephalic sites of progesterone action for inhibiting aggression and facilitating sexual receptivity in estrogen-primed golden hamsters
39. A receptor complex at the pituitary level
40. A receptor stimulation during the estrous cycle of the rat
41. Differential localization of progesterone uptake in brain: Role of sex, estrogen pretreatment and adrenalectomy
42. Influences of gender, gonadectomy, and estrous cycle on GABA/BZ receptors and benzodiazepine responses in rats