Chondrocyte-derived ezrin-like domain containing protein (CDEP), a rho guanine nucleotide exchange factor, is inducible in chondrocytes by parathyroid hormone and cyclic AMP and has transforming activity in NIH3T3 cells

Osteoarthritis and Cartilage

Volumn 9, Issue SUPPL. A, 2001, Pages

  Koyano, Y ^a,b   Kawamoto, T ^a   Kikuchi, A ^c   Shen, M ^a   Kuruta, Y ^d   Tsutsumi, S ^a   Fujimoto, K ^a   Noshiro, M ^a   Fujii, K ^b   Kato, Y ^d  

^a HIROSHIMA UNIVERSITY   (Japan)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

Chondrocyte; GEF; PTH; Rho

Indexed keywords

BUCLADESINE; COMPLEMENTARY DNA; CYCLIC AMP; EZRIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE; MESSENGER RNA; PARATHYROID HORMONE; RHO FACTOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TRITIUM;

ANIMAL CELL; ARTICLE; CARTILAGE CELL; CELL CULTURE; CELL LYSATE; CELL MATURATION; CELL STRAIN 3T3; CELL TRANSFORMATION; CONTROLLED STUDY; DISSOCIATION; GENETIC TRANSFECTION; GROWTH PLATE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0034854773     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1053/joca.2001.0446     Document Type: Article

References (14)

1. Effects of parathyroid hormone and calcitonin on alkaline phosphatase activity and matrix calcification in rabbit growth-plate chondrocyte cultures
2. Changes in parathyroid hormone receptors during chondrocyte cytodifferentiation
3. Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene
4. Effects of cyclic adenosine 3′,5′-monophosphate on chondrocyte terminal differentiation and cartilage-matrix calcification
5. Molecular characterization of the novel basic helix-loop-helix protein DEC1 expressed in differentiated human embryo chondrocytes
6. Molecular cloning and characterization of CDEP, a novel human protein containing the ezrin-like domain of the band 4.1 superfamily and the Dbl homology domain of Rho guanine nucleotide exchange factors
7. Rho GTPases and signaling networks
8. Dbl family proteins
9. Osteogenesis by chondrocytes from growth cartilage of rat rib
10. Post-translational modifications of Ras and Ral are important for the action of Ral GDP dissociation stimulator
11. Guanine nucleotide exchange catalyzed by dbl oncogene product
12. Biological assays for cellular transformation
13. Cell transformation by dbl oncogene
14. Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein