Multiple endocrine neoplasia type IIA: Report of a family with a study of three generations in Qatar

Endocrine Practice

Volumn 7, Issue 1, 2001, Pages 19-27

  Zirie, M ^a   Mohammed, I ^a   El Emadi, M ^a   Haider, A ^a  

^a HAMAD GENERAL HOSPITAL   (Qatar)

Author keywords

[No Author keywords available]

Indexed keywords

(3 IODOBENZYL)GUANIDINE; (3 IODOBENZYL)GUANIDINE I 131; ADRENALIN; ALANINE AMINOTRANSFERASE; ALBUMIN; CALCITONIN; CALCITRIOL; CALCIUM; CARCINOEMBRYONIC ANTIGEN; CATECHOLAMINE; CONTRAST MEDIUM; CYTOSINE; DOPAMINE; GUANINE; HYDROCORTISONE; LEVOTHYROXINE; LIOTHYRONINE; MAGNESIUM; MEDRONATE TECHNETIUM TC 99M; METADRENALIN; NORADRENALIN; PARATHYROID HORMONE; PENTAGASTRIN; PERTECHNETIC ACID TC 99M; PRAZOSIN; THYMINE; THYROTROPIN; THYROXINE; UNINDEXED DRUG; VANILMANDELIC ACID; ONCOPROTEIN; PROTEIN TYROSINE KINASE; PROTO ONCOGENE PROTEINS; PROTO ONCOGENE PROTEINS RET; PROTO-ONCOGENE PROTEINS RET;

ADRENALECTOMY; ADULT; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CALCIUM BLOOD LEVEL; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; CLINICAL STUDY; CODON; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DISEASE CLASSIFICATION; FAMILY HEALTH; FAMILY STUDY; FEMALE; FOLLOW UP; GENE MUTATION; GENETIC ANALYSIS; GENETIC SCREENING; HEREDITY; HUMAN; HYPERPARATHYROIDISM; LIVER METASTASIS; LYMPH NODE METASTASIS; MALE; PARATHYROID HYPERPLASIA; PHEOCHROMOCYTOMA; POSTOPERATIVE CARE; PROTO ONCOGENE; PROVOCATION TEST; QATAR; RADIODIAGNOSIS; RELATIVE; SIPPLE SYNDROME; THYROID MEDULLARY CARCINOMA; THYROID SCINTISCANNING; THYROIDECTOMY; URINALYSIS; ADRENAL TUMOR; BLOOD; CASE REPORT; ECHOGRAPHY; GENETICS; HYPERPLASIA; INFANT; LIVER TUMOR; MEDULLARY CARCINOMA; METASTASIS; MUTATION; PARATHYROID GLAND; PATHOLOGY; PEDIGREE; PRESCHOOL CHILD; THYROID TUMOR;

ADRENAL GLAND NEOPLASMS; ADULT; CALCITONIN; CARCINOMA, MEDULLARY; CASE REPORT; CHILD; CHILD, PRESCHOOL; CODON; FEMALE; HUMAN; HYPERPLASIA; INFANT; LIVER NEOPLASMS; LYMPHATIC METASTASIS; MALE; MIDDLE AGE; MULTIPLE ENDOCRINE NEOPLASIA TYPE 2A; MUTATION; PARATHYROID GLANDS; PEDIGREE; PHEOCHROMOCYTOMA; PROTO-ONCOGENE PROTEINS; QATAR; RECEPTOR PROTEIN-TYROSINE KINASES; THYROID NEOPLASMS; THYROIDECTOMY;

EID: 0034854075     PISSN: 1530891X     EISSN: None     Source Type: Journal    
DOI: 10.4158/ep.7.1.19     Document Type: Article

References (46)

1. Study of a kindred with pheochromocytoma, medullary thyroid carcinoma, hyperparathyroidism and Cushing's disease: Multiple endocrine neoplasia, type 2
2. Changing concepts in the diagnosis and management of thyroid nodules
3. Management of thyroid nodules, another look
4. Evaluation and management of the solid thyroid nodule
5. Fine-needle aspiration cytology in the preoperative diagnosis of thyroid nodules
6. Fine needle aspiration cytologic study of the solitary thyroid nodule: Profile of 308 cases with histologic correlation
7. Evaluation of the fine needle aspiration biopsy in the preoperative selection of cold thyroid nodules
8. Pathology of multiple endocrine neoplasias 2A and 2B: A review
9. Routine measurement of serum calcitonin in nodular thyroid diseases allows the preoperative diagnosis of unsuspected sporadic medullary thyroid carcinoma
10. Prevalence of sporadic medullary thyroid carcinoma: The importance of routine measurement of serum calcitonin in the diagnostic evaluation of thyroid nodules
11. Should serum calcitonin be measured routinely in all patients with nodular thyroid disease?
12. Interest of routine measurement of serum calcitonin: Study in a large series of thyroidectomized patients
13. Current diagnosis and management of medullary thyroid carcinoma
14. Germline RET mutations in MEN 2A and FMTC and their detection by simple DNA diagnostic tests
15. Genetic testing in the diagnosis and management of multiple endocrine neoplasia type II
16. Direct, non-radioactive detection of mutations in multiple endocrine neoplasia type 2A families
17. The association of pheochromocytoma with carcinoma of the thyroid gland
18. Genotype-phenotype correlation in multiple endocrine neoplasia type 2: Report of the International RET Mutation Consortium
19. A linked genetic marker for multiple endocrine neoplasia type 2A on chromosome 10
20. Assignment of multiple endocrine neoplasia type 2A to chromosome 10 by linkage
21. Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A
22. Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC
23. Specific mutations of the RET proto-oncogene are related to disease phenotype in MEN 2A and FMTC
24. Genetic screening for multiple endocrine neoplasia type 2
25. Advances in genetic screening for multiple endocrine neoplasia type 2 and the implications for management of children at risk
26. Clinical use of molecular information in the management of multiple endocrine neoplasia type 2A
27. RET proto-oncogene mutations in French MEN 2A and FMTC families
28. The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2: International RET Mutation Consortium analysis
29. C-cell hyperplasia preceding medullary thyroid carcinoma
30. The clinical outcome of prospective screening for multiple endocrine neoplasia type 2A: An 18-year experience
31. Age-related probability of development of hereditary medullary thyroid carcinoma
32. Results of early thyroidectomy for medullary thyroid carcinoma in children with multiple endocrine neoplasia type 2
33. Provocative testing for occult medullary carcinoma of the thyroid: Findings in seven children with multiple endocrine neoplasia type IIA
34. New approaches to the patient with medullary carcinoma of the thyroid gland
35. Predictive DNA testing and prophylactic thyroidectomy in patients at risk for multiple endocrine neoplasia, type 2A
36. In-octreotide and 99mTc(V)-dimercaptosuccinic acid studies in the imaging of recurrent medullary thyroid carcinoma
37. Selective venous sampling catheterisation for localisation of persisting medullary thyroid carcinoma
38. Reoperation for recurrent or persistent medullary thyroid cancer
39. Progression of postoperative residual medullary thyroid carcinoma as monitored by plasma calcitonin levels
40. Long-term course of patients with persistent hypercalcitoninemia after apparent curative primary surgery for medullary thyroid carcinoma
41. Medullary thyroid cancer: Analyses of survival and prognostic factors and the role of radiation therapy in local control
42. Chemotherapy with dacarbazine and 5-fluorouracil in advanced medullary thyroid cancer
43. Treatment of advanced medullary thyroid carcinoma with a combination of cyclophosphamide, vincristine, and dacarbazine
44. Long-term results in 64 patients operated upon for pheochromocytoma
45. Pheochromocytoma in multiple endocrine neoplasia type 2A: Survey of 100 cases
46. Pheochromocytoma in multiple endocrine neoplasia type 2: European study