Inhibition of bloodstream form Trypanosoma brucei gene expression by RNA interference using the pZJM dual T7 vector

Molecular and Biochemical Parasitology

Volumn 117, Issue 1, 2001, Pages 111-113

  Morris, James C ^a   Wang, Zefeng ^a   Drew, Mark E ^a   Paul, Kimberly S ^a   Englund, Paul T ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Gene regulation; p34 37; RNA interference; Trypanosoma brucei

Indexed keywords

HYGROMYCIN; PHLEOMYCIN; RECOMBINANT DNA; RIBOSOME DNA; RNA BINDING PROTEIN; TETRACYCLINE; VIRUS VECTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; AUTORADIOGRAPHY; CELL GROWTH; CELL LINE; CONTROLLED STUDY; DNA HYBRIDIZATION; EXPRESSION VECTOR; GENE EXPRESSION; GENE SILENCING; GENETIC ANALYSIS; GENETIC TRANSFECTION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM; STEADY STATE; TRYPANOSOMA BRUCEI;

ANIMALIA; EUKARYOTA; TRYPANOSOMA; TRYPANOSOMA BRUCEI;

EID: 0034853633     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(01)00334-6     Document Type: Article

References (7)

1. Double-stranded RNA induces mRNA degradation in Trypanosoma brucei
2. Inhibition of Trypanosoma brucei gene expression by RNA interference using an integratable vector with opposing T7 promoters
3. Developmental regulation of two nuclear RNA binding proteins, p34 and p37, from Trypanosoma brucei
4. Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers
5. DNA-mediated transformation of bloodstream-form Trypanosoma brucei
6. Inducible gene expression in trypanosomes mediated by a prokaryotic repressor
7. Vectors for inducible expression of toxic gene products in bloodstream and procyclic Trypanosoma brucei