Macrophage-oriented cytotoxic activity of novel triterpene saponins extracted from roots of Securidaca inappendiculata

International Immunopharmacology

Volumn 1, Issue 11, 2001, Pages 1989-2000

  Yui, Satoru ^a   Ubukata, Kazuyoshi ^a   Hodono, Kazumi ^a   Kitahara, Mikio ^b   Mimaki, Yoshihiro ^c   Kuroda, Minpei ^c   Sashida, Yutaka ^c   Yamazaki, Masatoshi ^a  

^a TEIKYO UNIVERSITY   (Japan)

^b KANEKA CORPORATION   (Japan)

^c TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Apoptosis; M CSF; Macrophages; Saponin compounds

Indexed keywords

3,4 DIMETHOXYCINNAMIC ACID; COLONY STIMULATING FACTOR 1; CONCANAVALIN A; DNA NUCLEOTIDYLEXOTRANSFERASE; GRANULOCYTE COLONY STIMULATING FACTOR; HOT WATER; SAPONIN; SECURIOSIDE A; SECURIOSIDE B; TRITERPENE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL DEATH; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOSTASIS; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG POTENCY; DRUG STRUCTURE; GROWTH INHIBITION; MALE; MOUSE; NICK END LABELING; NONHUMAN; PLANT ROOT; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; THYMOCYTE; TUMOR CELL LINE;

ANIMALS; CELL DEATH; CELLS, CULTURED; IN SITU NICK-END LABELING; INDICATORS AND REAGENTS; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES; MALE; MICE; MICE, INBRED C3H; PLANT EXTRACTS; PLANT ROOTS; PLANTS, MEDICINAL; POLYGALACEAE; SAPONINS; TETRAZOLIUM SALTS; THIAZOLES; TRITERPENES;

EID: 0034852043     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1567-5769(01)00126-6     Document Type: Article

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